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Haegarda

Generic Name: complement C1 esterase inhibitor (KOM ple ment C1 ES ter ase in HIB it or)
Brand Name: Haegarda

Medically reviewed by Drugs.com on Nov 26, 2018 – Written by Cerner Multum

What is Haegarda?

Haegarda is a man-made form of a protein in blood that helps control swelling in the body. People with a condition called hereditary angioedema do not have enough of this protein. Hereditary angioedema can cause attacks of swelling and symptoms such as stomach problems or trouble breathing.

Haegarda is used in people with hereditary angioedema.

Haegarda may also be used for purposes not listed in this medication guide.

Important Information

You should not use Haegarda if have ever had a life-threatening allergic reaction to Haegarda.

Before taking this medicine

You should not use this medicine if have ever had a life-threatening allergic reaction to Haegarda.

Tell your doctor if you have ever had:

  • a stroke or blood clot;

  • heart problems; or

  • an "in-dwelling" catheter.

Tell your doctor if you are pregnant or breast-feeding.

Haegarda is made from donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.

How should I use Haegarda?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Haegarda is injected under the skin. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.

Read and carefully follow any Instructions for Use provided with your medicine. Prepare an injection only when you are ready to give it. Ask your doctor or pharmacist if you don't understand all instructions.

Seek emergency medical attention after using Berinert to treat an angioedema attack.

Storing unopened vials: Store in a refrigerator or at cool room temperature and use until expiration date. Protect from light and do not freeze.

Each vial (bottle) is for one use only. Throw it away after one use, even if there is still medicine left inside.

After mixing Haegarda, use the injection right away or store at room temperature and use within 8 hours.

Haegarda contains no preservative. Once you have pierced the rubber top of a vial with a needle, you must use that vial right away or throw it away.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose of Haegarda.

Keep Haegarda on hand at all times to prevent angioedema, especially while traveling.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid after using Haegarda?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Haegarda side effects

Get emergency medical help if you have signs of an allergic reaction: hives; chest tightness, fast heartbeats, feeling light-headed; wheezing or difficult breathing, blue lips or gums; or swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • sudden numbness or weakness on one side of the body;

  • pain, swelling, warmth, or redness in an arm or leg;

  • sudden severe headache, confusion, problems with vision, speech, or balance;

  • chest pain while taking deep breaths; or

  • fast heart rate.

Common side effects may include:

  • unusual or unpleasant taste in your mouth;

  • headache, dizziness;

  • nausea, vomiting;

  • pain, bruising, itching, swelling, bleeding, warmth, or a hard lump where the medicine was injected;

  • stuffy nose, sore throat;

  • rash; or

  • fever.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Haegarda?

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may affect Haegarda, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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