What is Alprolix?
Alprolix is a man-made protein similar to a natural protein in the body that helps the blood to clot.
Alprolix may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use this medicine if:
you have had an allergic reaction to clotting factor medicine;
you have signs of excessive blood clotting; or
you are allergic to hamster proteins.
To make sure Alprolix is safe for you, tell your doctor if you have ever had:
a heart attack or stroke.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether Alprolix passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Alprolix is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.
How should I use Alprolix?
Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Your doctor may want to give your first dose of this medicine in a hospital or clinic setting to quickly treat any serious side effects that occur.
Alprolix is injected into a vein through an IV. You may be shown how to use an IV at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used.
Alprolix is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.
The mixture should appear clear, yellow, or colorless. Do not use the mixed medicine if it has changed colors or has particles in it. Prepare a new kit or call your pharmacist for a new supply of Alprolix.
Gently swirl but do not shake the medicine bottle when mixing or you may ruin the medicine. Use the injection within 3 hours after mixing your dose.
Alprolix comes with patient instructions for proper mixing and storage. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Use a disposable needle only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.
While using Alprolix, you may need frequent blood tests.
If you store this medicine at home, carefully follow the directions on your medicine label about how to store the powder medicine and the diluent. Some forms of Alprolix can be stored at room temperature, and others should be kept in a refrigerator. Do not freeze. Avoid exposing the medication to light.
Each single-use vial (bottle) of this medicine is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose.
Throw away any Alprolix not used before the expiration date on the medicine label.
What happens if I miss a dose?
Call your doctor for instructions if you miss a dose of this medicine.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using Alprolix?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Alprolix side effects
Get emergency medical help if you have signs of an allergic reaction: hives, itching; wheezing, tightness in your chest, difficult breathing, fast heartbeats, blue lips, feeling like you might pass out; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
swelling in your hands, feet, or ankles;
swelling in your waist, weight gain;
loss of appetite;
fever or chills;
continued bleeding after treatment;
new or worsened bleeding; or
signs of excessive blood clotting--sudden numbness or weakness (especially on one side of the body), slurred speech, problems with vision or balance, chest pain, coughing up blood, or pain, swelling, warmth and redness in one or both legs.
Common side effects may include:
altered sense of taste;
mild skin rash; or
pain, redness, itching, stinging, or other irritation where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Alprolix?
Other drugs may interact with coagulation factor IX, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
More about Alprolix (coagulation factor ix)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 0 Reviews – Add your own review/rating
- Drug class: miscellaneous coagulation modifiers
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about Alprolix.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 3.03.
Last reviewed: December 28, 2017
Date modified: February 01, 2018