How is Empaveli administered?
Empaveli (pegcetacoplan) is given subcutaneously (this means under the skin) using the Empaveli injector or an infusion pump.
The Empaveli injector is self-administered and is a compact, wearable, circular device that is placed on your stomach at least 1 inch from your belly button or previous injection site. The device has an adhesive side that allows it to be firmly attached to your stomach. No needle or tubing can be seen, and it can be worn under loose clothing, which allows the person to be mobile and continue light daily activities without having to sit still waiting for the infusion to finish. The injection is started by removing a safety tab and pressing a button on the device, and takes around 30 to 60 minutes to complete. Your doctor or nurse will show you how to use the injector so you can administer it at home, or a caregiver can administer it to you.
Empaveli can also be given subcutaneously by a healthcare provider as an infusion into a clear area of skin on a person’s stomach (avoiding the belly button), top of the thighs, hips, or upper arms.
References
- Empaveli (pegcetacoplan) Updated 10/2023. Apellis Pharmaceuticals, Inc. https://www.drugs.com/pro/empaveli.html
- Instructions for Use. Empaveli Injector. https://pi.apellis.com/files/IFU_EMPAVELIinjector.pdf
- Paroxysmal Nocturnal Hemoglobinuria (PNH) The Sidney Kimmel Comprehensive Cancer Center. John Hopkins Medicine. https://www.hopkinsmedicine.org/kimmel_cancer_center/types_cancer/paroxysmal_nocturnal_hemoglobinuria_PNH.html#:~:text=Paroxysmal%20nocturnal%20hemoglobinuria%20(PNH)%20is,of%20the%20three%20blood%20components).
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