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In the US, Orphenadrine (orphenadrine systemic) is a member of the drug class skeletal muscle relaxants and is used to treat Migraine and Muscle Spasm.

US matches:

UK matches:



CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Treatment of Parkinson's disease

Muscarinic receptor antagonist, centrally acting

Muscle relaxant, centrally acting

Chemical Name

Etanamine, N,N-dimetyl-2-[(2-metylphenyl)phenylmetoxy]-

Foreign Names

Generic Names

Brand Names

  • Belmalen (Orphenadrine and Diclofenac)
    Cetus, Argentina
  • Doloctaprin
    Medco, Peru
  • Dolo-Quimagésico (Orphenadrine and Diclofenac)
    Farmindustria, Peru
  • Dolo-Quimagésico Flex (Orphenadrine and Diclofenac)
    Farmindustria, Peru
  • Dolotrineural (Orphenadrine and Diclofenac)
    Medco, Peru
  • Efagesic (Orphenadrine and Paracetamol)
    Farmaceutica Latina, Peru
  • Mialgin
    Cipa, Peru
  • Miodolfenex (Orphenadrine and Diclofenac)
    Iqfarma, Peru
  • Neodolpaze (Orphenadrine and Diclofenac)
    Fresenius Kabi, Bosnia & Herzegowina
  • Norflex
    3m healthcare, Egypt; Eipico, Egypt; Farmindustria, Peru
  • Norflex Plus (Orphenadrine and Paracetamol)
    Farmindustria, Peru
  • Norgesic (Orphenadrine and Paracetamol)
    Eipico, Egypt
  • Orfenadrina
    Farmindustria, Peru; LCG, Peru; Marfan, Peru; Refasa, Peru
  • Orphamol (Orphenadrine and Orphenadrine)
    Rameda, Egypt
  • Orphenadrine plus (Orphenadrine and Paracetamol)
    Alexandria Co., Egypt
  • Orphipal
    GlaxoSmithKline, India
  • Phemax
    Central Poly, Thailand
  • Pleren
    Pharmalab, Peru
  • Pleren (Orphenadrine and Paracetamol)
    Pharmalab, Peru
  • Pleren Plus (Orphenadrine and Paracetamol)
    Pharmalab, Peru
  • Redex Plus (Orphenadrine and Diclofenac)
    Magma, Peru
  • Relaxophen
    Kahira, Egypt
  • Rexalgan
    Infarmasa, Peru
  • Acetor (Orphenadrine and Paracetamol)
    Neomedix, Pakistan
  • AN-AN (Orphenadrine and Paracetamol)
    AND, Taiwan
  • Anarex (Orphenadrine and Paracetamol)
    CCM, Malaysia
  • Angesic (Orphenadrine and Paracetamol)
    Mass Pharma, Pakistan
  • Anliton (Orphenadrine and Paracetamol)
    Fu Seng, Taiwan
  • Anorol (Orphenadrine and Paracetamol)
    Medera, Pakistan
  • Banflex
    Forest, United States
  • Begesic (Orphenadrine and Paracetamol)
    Batala Pharma, Pakistan
  • Besemax (Orphenadrine and Paracetamol)
    Al Pharm, South Africa
  • Caditar Flex (Orphenadrine and Celecoxib)
    Farmindustria, Peru
  • Cetagesic (Orphenadrine and Paracetamol)
    CCM Duopharma Biotech, Malaysia
  • Corilax (Orphenadrine and Paracetamol)
    Community Pharm PCL, Thailand
  • Dolan
    Eng City, Taiwan
  • Dolan (Orphenadrine and Paracetamol)
    Takeda, Finland
  • Dorpane (Orphenadrine and Paracetamol)
    MacroPhar, Thailand
  • Duragesic (Orphenadrine and Paracetamol)
    Tabros, Myanmar
  • Flexon
    Keene, United States
  • Medgesic (Orphenadrine and Paracetamol)
    Medifive, Thailand
  • Modron (Orphenadrine and Paracetamol)
    Tai Yu, Taiwan
  • Muscadol (Orphenadrine and Paracetamol)
    Julphar, Oman
  • Muscerol (Orphenadrine and Paracetamol)
    Pharmaline, Lebanon
  • Muscol (Orphenadrine and Paracetamol)
    Teva, Israel
  • Myodrine (Orphenadrine and Paracetamol)
    Charoen Bhaesaj Lab, Thailand
  • Myoflex (Orphenadrine and Paracetamol)
    Siam Bheasach, Thailand
  • Myogesic (Orphenadrine and Paracetamol)
    Dar Al Dawa, Oman
  • Myosic (Orphenadrine and Paracetamol)
    Atlantic Lab, Hong Kong
  • Mypara Plus Orphenadrine (Orphenadrine and Paracetamol)
    Greater Pharma, Thailand
  • Nabesac (Orphenadrine and Paracetamol)
    Masa Lab, Thailand
  • Neodolpasse (Orphenadrine and Diclofenac)
    Fresenius, Hungary; Fresenius, Romania; Fresenius, Slovakia; Fresenius Kabi, Bulgaria; Fresenius Kabi, Croatia (Hrvatska); Fresenius Kabi Austria, Austria
  • Neodolpasse (Orphenadrine and Orphenadrine)
    Fresenius Kabi, Czech Republic
  • Norflex
    3M, United States; Bausch & Lomb Pharma, Thailand; Graceway, Costa Rica; Graceway, Dominican Republic; Graceway, Guatemala; Graceway, Honduras; Graceway, Panama; Graceway, El Salvador; Graceway, United States; iNova, Australia; iNova, Malaysia; iNova, New Zealand; iNova, Taiwan; iNova, South Africa; Meda, Finland; Meda, Sweden; Meda Pharm, Greece; MEDA Pharma, Germany; Valeant Pharmaceuticals International, Canada
  • Norflex CO (Orphenadrine and Paracetamol)
    iNova, South Africa
  • Norgesic (Orphenadrine and Paracetamol)
    Bausch & Lomb Pharma, Thailand; iNova, Australia; iNova, Hong Kong; iNova, Malaysia; iNova, Philippines; iNova, Taiwan; Inova Pharmaceuticals, Lebanon; Meda, Finland; Meda, Iceland; Meda, Malta; Meda, Sweden; Meda Pharm, Austria; Meda Pharm, Greece; More Pharma Corporation, Costa Rica; More Pharma Corporation, Dominican Republic; More Pharma Corporation, Guatemala; More Pharma Corporation, Honduras; More Pharma Corporation, Panama; More Pharma Corporation, El Salvador
  • Norgetex (Orphenadrine and Paracetamol)
    Medinova, Myanmar
  • Norphen (Orphenadrine and Paracetamol)
    Atlantic Lab, Thailand
  • Nuosic (Orphenadrine and Paracetamol)
    Millimed, Thailand
  • Nurasic (Orphenadrine and Paracetamol)
    T.O. Chemicals, Thailand
  • Opheryl
    Saehan, South Korea
  • Orano (Orphenadrine and Paracetamol)
    Unison, Thailand
  • Orcigesic (Orphenadrine and Mefenamic Acid)
    Sunward Pharmaceutical, Singapore
  • Orfenace
    SteriMax, Canada
  • Orfenaflex
    Paill, Guatemala; Paill, Honduras; Paill, Nicaragua; Paill, El Salvador
  • Orfenaflex-D (Orphenadrine and Diclofenac)
    Paill, Dominican Republic; Paill, Honduras; Paill, Panama; Paill, El Salvador
  • Orflex
    Gentle, Taiwan
  • Orkelax (Orphenadrine and Paracetamol)
    Kenyaku, Thailand; Schumit, Thailand
  • Orphenadrine Apothecon
    Apothecon, United States
  • Orphenadrine Citrate Actavis
    Actavis, United States
  • Orphengesic (Orphenadrine and Paracetamol)
    Bangkok Lab & Cosmetic, Thailand
  • Orphensic (Orphenadrine and Paracetamol)
    General Drugs House, Thailand
  • Paranadrine (Orphenadrine and Paracetamol)
    Shou Chan, Taiwan
  • Pormus (Orphenadrine and Paracetamol)
    Unison, Hong Kong; Unison, Thailand
  • Relaflex
    Vijosa, Belize; Vijosa, Guatemala; Vijosa, Honduras; Vijosa, Nicaragua; Vijosa, El Salvador
  • Sandoz Orphenadrine
    Sandoz, Canada
  • Sinsolax (Orphenadrine and Paracetamol)
    Synmosa, Taiwan
  • Sonchi (Orphenadrine and Paracetamol)
    Panion & BF, Taiwan
  • Tensionlex
    Panbiotic, Taiwan
  • Zinpin
    Swiss Pharm, Taiwan
  • Disipal
    Alapis Pharma, Greece; Astellas Pharma, United Kingdom; bioCSL, New Zealand; iNova, South Africa
  • Lysantin
    Medic, Denmark
  • Orfenadrine HCl CF
    Centrafarm, Netherlands
  • Orfenal
    Remedica, Malta
  • Orphenadrine Hydrochloride Rosemont
    Rosemont Pharmaceuticals, United Kingdom


BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.