Buprenorphine (International)
Note: In some countries, this medicine may only be approved for veterinary use.
In the US, Buprenorphine (buprenorphine systemic) is a member of the drug class Opioids (narcotic analgesics) and is used to treat Chronic Pain, Opiate Dependence - Induction, Opiate Dependence - Maintenance, Opioid Use Disorder and Pain.
US matches:
- Buprenorphine
- Buprenorphine and naloxone oral/sublingual
- Buprenorphine buccal
- Buprenorphine/naloxone
- Buprenorphine and Naloxone Buccal Film
- Buprenorphine and Naloxone Sublingual Film (Suboxone)
- Buprenorphine and Naloxone Sublingual Tablets
- Buprenorphine Buccal Film
- Buprenorphine Injection
- Buprenorphine Patch
- Buprenorphine Sublingual
- Buprenorphine and Naloxone Sublingual Film
Scheme
Rec.INN
ATC (Anatomical Therapeutic Chemical Classification)
N02AE01,N07BC01,N07BC51
CAS registry number (Chemical Abstracts Service)
0052485-79-7
Chemical Formula
C29-H41-N-O4
Molecular Weight
468
Therapeutic Category
Opioid analgesic
Chemical Names
(5R,6R,6R,7R,9R,13S,14S)-17-Cyclopropylmetyl-7-[(S)-3,3-dimetyl-2-hydroxybutan-2-yl-]-6-metoxy-4,5-epoxy-6,14-etanomorphinan-3-ol (IUPAC)
21-Cyclopropyl-7alpha-[(S)-1-hydroxy-1,2,2-trimetylpropyl]-6,14-endo-etano-6,7,8,14-tetrahydrooripavine (WHO)
6,14-Etenomorphinan-7-metanol, 17-(cyclopropylmetyl)-α-(1,1-dimetyletyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-metoxy-α-metyl-, [5α,7α(S)]-
Foreign Names
- Buprenorphinum (Latin)
- Buprenorphin (German)
- Buprénorphine (French)
- Buprenorfina (Spanish)
Generic Names
- Buprenorfina (OS: DCIT)
- Buprenorphine (OS: BAN, JAN)
- Buprénorphine (OS: DCF)
- 6029-M (ReckittColma) (IS)
- Buprenorphin (PH: Ph. Eur. 9)
- Buprenorphine (PH: BP 2018, Ph. Eur. 9, USP 41)
- Buprénorphine (PH: Ph. Eur. 9)
- Buprenorphinum (PH: Ph. Eur. 9)
- Buprenorphine Hydrochloride (OS: BANM, USAN, JAN)
- CL 112302 (Lederle) (IS)
- NIH 8805 (IS)
- RX 6029-M (ReckittColma) (IS)
- UM 952 (IS)
- Buprénorphine (chlorhydrate de) (PH: Ph. Eur. 9)
- Buprenorphine Hydrochloride (PH: BP 2018, JP XVII, USP 41)
- Buprenorphine hydrochloride (PH: Ph. Eur. 9)
- Buprenorphinhydrochlorid (PH: Ph. Eur. 9)
- Buprenorphini hydrochloridum (PH: Ph. Eur. 9)
Brand Names
- Addnok
Activase Pharmaceuticals, Slovenia; Rusan, India - Addnok-N [+ Naloxone]
Rusan Pharma Ltd., Georgia - Astec 35 µg/h
Gebro Pharma, Austria - Astec 52,5 µg/h
Gebro Pharma, Austria - Astec 70 µg/h
Gebro Pharma, Austria - Bugnanto
Sandoz, Norway - Bulnexo [+ Naloxone]
ALKALOID - INT, Slovenia - Bunalict [+ Naloxon]
Sandoz, Norway; Sandoz, Slovenia - Bunavail [+ Naloxone]
BDSI, United States - Bunondol
Warszawskie Zaklady Farmaceutyczne Polfa, Lithuania - Bunorfin
Gebro, Spain - BUP-4 Tagepflaster Libra-Pharm
Libra-Pharm, Germany - Bupain
Sandoz, Croatia (Hrvatska) - Bupeaze
Dr. Reddy's, United Kingdom - Bupensan
G.L. Pharma, Lithuania - Buplast
Generics UK, United Kingdom - Bupramyl
Generics UK, United Kingdom - Bupredermal
Mundipharma, Australia - Bupredine 0.3 mg/ml [veterinary use]
Le Vet, Netherlands - Buprefarm
Orifarm Generics, Denmark; Orifarm Generics, Norway; Orifarm Generics, Sweden - Bupremyl
Mylan, Sweden - Bupren
Lafedar, Argentina - Buprenal
Viogen, Greece - Buprenorfin Alkaloid
Alkaloid, Serbia - Buprenorfin Mylan
Generics, Czech Republic - Buprenorfin Sandoz
Sandoz, Croatia (Hrvatska) - Buprenorfina Acino
Gebro, Spain - Buprenorfina Aurovitas
Generis, Portugal - Buprenorfina Ciclum
Ciclum, Portugal - Buprenorfina Ratiopharm
Ratiopharm, Spain; Ratiopharm, Portugal - Buprenorfina Sandoz
Sandoz España, Spain - Buprenorfina Stada
STADA, Spain - Buprenorfina Teva
Teva, Spain; Teva Pharmaceuticals, Poland - Buprenorfine CF
Centrafarm, Netherlands - Buprenorfine Glenmark
Glenmark Pharmaceuticals Europe Limited, Netherlands - Buprenorfine Mylan
Mylan, Netherlands - Buprenorfine Ranbaxy
Ranbaxy, Netherlands - Buprenorfine Sandoz
Sandoz, Belgium; Sandoz, Netherlands - Buprenorfine Teva
Teva Nederland, Netherlands; Teva Pharma Belgium, Belgium - Buprenorphin
Sandoz Pharmaceuticals d.d., Greece - Buprenorphin - 1 A Pharma
1A Pharma, Malta - Buprenorphin Actavis
Actavis, Bulgaria - Buprenorphin Actavis 20mg
Actavis, Bulgaria - Buprenorphin Actavis 30mg
Actavis, Bulgaria - Buprenorphin Actavis 40mg
Actavis, Bulgaria - Buprenorphin AL
Aliud Pharma, Germany - Buprenorphin Aristo
Aristo Pharma, Germany - Buprenorphin AWD
Teva, Germany - Buprenorphin beta
Betapharm, Germany - Buprenorphin Glenmark
Glenmark, Germany - Buprenorphin Mylan
Mylan dura, Germany - Buprenorphin ratiopharm 35 μ/h
ratiopharm Arzneimittel, Austria - Buprenorphin ratiopharm 52.5 μ/h
ratiopharm Arzneimittel, Austria - Buprenorphine
Nisshin Pharmaceutical, Japan - Buprenorphine Actavis
Actavis, Czech Republic - Buprenorphine Glenmark
Glenmark, Sweden; Glenmark Pharmaceuticals Nordic, Denmark - Buprenorphine Hexal
Hexal, Sweden - Buprenorphine Martindale
Martindale, Malta - Buprenorphine Orion
Orion Pharma, Sweden - Buprenorphine Sandoz
Sandoz, Czech Republic; Sandoz, Denmark; Sandoz, Norway; Sandoz, Sweden; Sandoz, Slovakia - Buprenorphine Sandoz 20mg
Hexal, Bulgaria - Buprenorphine Sandoz 30mg
Hexal, Bulgaria - Buprenorphine Sandoz 40mg
Hexal, Bulgaria - Buprenorphine Stada
STADA Nordic, Sweden - Buprenorphine Teva
Teva, Sweden - Buprenorphin-Mepha
Mepha Pharma, Switzerland - Buprenorphin-neuraxpharm
neuraxpharm Arzneimittel, Germany - Buprenorphin-ratiopharm
ratiopharm, Germany - Bupretec
G.L. Pharma, Poland; G.L.Pharma GmbH, Slovakia - Bupretec 52.5 μ/h
G.L. Pharma, Austria - Bupretec 70 μ/h
G.L. Pharma, Austria - Buprinor
AstraZeneca, India - Busiete
Reckitt Benckiser, Malta - Butec
Qdem Pharmaceuticals, United Kingdom - Butrans
Mundipharma, Ireland; Napp Pharmaceuticals, United Kingdom; Purdue, United States - BuTrans
Mundipharma Pharmaceuticals, Netherlands; Purdue Pharma, Canada - Butrans 10
LTS Lohmann Therapie Systeme, Israel; Napp Pharmaceutical, Oman - Butrans 20
LTS Lohmann Therapie Systeme, Israel; Napp Pharmaceutical, Oman - Butrans 5
LTS Lohmann Therapie Systeme, Israel; Napp Pharmaceutical, Oman - Buvera
Rafarm, Greece - Cisterin
Rimsa, Mexico - Feliben
Gebro, Spain - Hapoctasin
Actavis UK, United Kingdom - Kennaf
Actavis Group, Poland - Laribon
Pliva, Croatia (Hrvatska) - Lepetan
Otsuka Pharmaceutical, Japan - Mitoren
Pliva, Croatia (Hrvatska) - Natzon
Morningside Healthcare, Malta - Nimedol
Pliva, Croatia (Hrvatska) - Noprex
Glenmark, Czech Republic; Glenmark, Slovakia - Norspan
Grünenthal, Germany; Grünenthal, Peru; Mundipharma, Australia; Mundipharma, China; Mundipharma, Denmark; Mundipharma, Estonia; Mundipharma, Spain; Mundipharma, Finland; Mundipharma, Hong Kong; Mundipharma, Japan; Mundipharma, Lithuania; Mundipharma, Norway; Mundipharma, New Zealand; Mundipharma, Philippines; Mundipharma, Sweden; Mundipharma A/S, Iceland; Mundipharma Pharmaceuticals, Vietnam; Norpharma, Poland - Norspan 10 µg/h
Mundipharma, Hungary - Norspan 20 µg/h
Mundipharma, Hungary - Norspan 5 µg/h
Mundipharma, Hungary - Norspan 7
Grünenthal, Colombia - Panitaz
Dr. Reddy's, United Kingdom - Ramatrix
Tecnimede, Portugal - Reletrans
Sandoz, United Kingdom - Relevtec
Sandoz, United Kingdom - Restiva
Mundipharma, Argentina; Mundipharma, Brazil - Sevodyne
Aspire Pharma, United Kingdom - Simbadol [veterinary use]
Zoetis, United States - Soloro
Grünenthal, Mexico - Sovenor
Mundipharma, Malaysia; Mundipharma, Singapore; Mundipharma, South Africa - Sublocade
Indivior, United States - Suboxone [+ Naloxone]
Indivior Europe, Latvia; Indivior U.K., Greece; RB Pharmaceuticals, Cyprus; Schering-D, Italy; Schering-Plough, Turkey - Suboxone 8mg/2mg [+ Naloxone]
RB Pharmaceuticals, Hungary - Subutex
Indivior, Norway - Temgesic
Schering-Plough, Tunisia - Transtec
BModesto, Netherlands; Formenti, Italy; Grünenthal, Bosnia & Herzegowina; Grünenthal, Belgium; Grünenthal, Colombia; Grünenthal, Czech Republic; Grünenthal, Ecuador; Grünenthal, Spain; Grünenthal, Mexico; Grünenthal, Netherlands; Grünenthal, Peru; Grünenthal, Poland; Grünenthal, Portugal; Grünenthal, Slovakia; Grünenthal Chilena, Chile; Mundipharma, Denmark; Mundipharma, Ireland; Napp Pharmaceuticals, United Kingdom; Stada, Croatia (Hrvatska) - Transtec 35µg/h
Grünenthal, Austria; Grünenthal, Switzerland; Grünenthal, Hungary; Grünenthal S.A., Luxembourg - Transtec 52.5µg/h
Grünenthal, Austria; Grünenthal, Switzerland; Grünenthal, Hungary; Grünenthal S.A., Luxembourg - Transtec 70µg/h
Grünenthal, Austria; Grünenthal, Switzerland; Grünenthal, Hungary; Grünenthal S.A., Luxembourg - Transtec PRO
Grünenthal, Germany - Vetergesic [veterinary use]
Ceva Sante Animale, Ireland - Vetergesic chiens, chats [veterinary use]
Sogeval Laboratoire, Belgium - Zubsolv [+ Naloxone]
Mundipharma, Slovenia - Addictex
Actavis Group, Cyprus - Addnok
Activase, Czech Republic - Belbuca
BDSI, United States - Bowielone [+ Naloxone]
Ethypharm, United Kingdom - Brospina
Pisa, Mexico - Buepron
Sami, Pakistan - Bunalict [+ Naloxon]
Sandoz, Netherlands - Bunondol
Polfa Warsaw, Latvia; Polfa Warszawa, Poland - Bunorfin
Atco, Pakistan; Molteni, Poland - Bupaq [veterinary use]
Richter Pharma, Estonia; Richter Pharma, Norway; Richter Pharma, Poland; Richter Pharma AG, Ireland; Richter Pharma Austria, United Kingdom; Salfarm, Sweden; Streuli Vet, Switzerland; Vetcare, Finland - Bupaq 0,3 mg/ml für Hunde und Katzen [veterinary use]
Richter Pharma, Austria - Bupaq 0.3 mg/ml voor honden en katten [veterinary use]
Richter Pharma, Netherlands - Bupaq 0.3mg/ml [veterinary use]
Virbac, France - Bupensan
G.L. Pharma, Estonia - Bupensan 2 mg
G.L. Pharma, Austria - Bupensan 4 mg
G.L. Pharma, Austria - Bupensan 8 mg
G.L. Pharma, Austria - Buprecare [veterinary use]
Animalcare, United Kingdom; Animalcare, Ireland - Buprecare 0.3 mg/ml voor honden en katten [veterinary use]
Animalcare, Netherlands - Buprecare 0.3mg/ml [veterinary use]
Axience, France - Bupredine [veterinary use]
Le Vet, Estonia; Le Vet Pharma B.V., United Kingdom - Bupredine vet [veterinary use]
Le Vet, Iceland - Bupredyne [veterinary use]
Jurox, Australia - Buprefelican [veterinary use]
Faunapharma, Finland; Le Vet Pharma B.V., United Kingdom - Bupregesic
Popular, Pakistan - Buprelieve [veterinary use]
Jurox UK plc, United Kingdom - Buprenaddict
Hexal, Germany - Buprenex
Reckitt Benckiser, United States - Buprenodale [veterinary use]
Albrecht, Germany; Dechra, Ireland; Dechra, Sweden; Dechra Veterinary Products, Belgium; Dechra Veterinary Products, United Kingdom - Buprenodale 0.3 mg/ml voor honden, katten en paarden [veterinary use]
Dechra Veterinary Products, Netherlands - Buprenodale 0.3mg/ml [veterinary use]
Dechra Veterinary Products, France - Buprenodale 0.3mg/ml für Hunde, Katzen und Pferde
Dechra, Austria - Buprenorfin
Alkaloid, Bosnia & Herzegowina; Lek, Bosnia & Herzegowina - Buprenorfin Actavis
Actavis, Sweden - Buprenorfin Alkaloid
Alkaloid, Croatia (Hrvatska); Alkaloid, Macedonia - Buprenorfina Azevedos
Azevedos, Portugal - Buprenorfina Goldfarma
Goldfarma, Portugal - Buprenorfine Mylan
Mylan, Netherlands - Buprenorfine SUN
Sun Pharma, Netherlands - Buprenorphin AbZ
AbZ-Pharma, Germany - Buprenorphin Actavis
Actavis, Denmark; PUREN Pharma, Germany - Buprenorphin dura
Mylan dura, Germany - Buprenorphin Ethypharm
Ethypharm, Germany - Buprenorphin G.L. 2mg
G.L. Pharma, Bulgaria; G.L. Pharma, Germany - Buprenorphin G.L. 4mg
G.L. Pharma, Bulgaria; G.L. Pharma, Germany - Buprenorphin G.L. 8mg
G.L. Pharma, Bulgaria; G.L. Pharma, Germany - Buprenorphin Hexal 2 mg
Hexal Pharma, Austria - Buprenorphin Hexal 8 mg
Hexal Pharma, Austria - Buprenorphin Puren
PUREN Pharma, Germany - Buprenorphin ratiopharm 2 mg
ratiopharm Arzneimittel, Austria - Buprenorphin ratiopharm 70 μ/h
ratiopharm Arzneimittel, Austria - Buprenorphin ratiopharm 8 mg
ratiopharm Arzneimittel, Austria - Buprenorphin Sanofi
Zentiva Pharma, Germany - Buprenorphine
Actavis UK, United Kingdom; I-Gen, Germany; Ranbaxy, United Kingdom; Shinlin Sinseng, Taiwan; Thornton & Ross, United Kingdom - Buprenorphine Alkaloid
Alkaloid, Czech Republic; Alkaloid, Poland - Buprenorphine Alkaloid 2 mg
Alkaloida, Hungary - Buprenorphine Alkaloid 8 mg
Alkaloida, Hungary - Buprénorphine Arrow
Arrow, France - Buprénorphine Biogaran
Biogaran, France - Buprenorphine Bluefish
Bluefish Pharma, Sweden - Buprénorphine Cristers
CristerS, France - Buprénorphine EG
EG Labo, France - Buprenorphine Ethypharm
Ethypharm, Sweden - Buprenorphine G.L. Pharma
Nordic Drugs, Sweden - Buprenorphine Morningside
Morningside Healthcare, Malta - Buprénorphine Mylan
Mylan, France - Buprenorphine Orifarm
Orifarm Generics, Denmark; Orifarm Generics, Norway; Orifarm Generics, Sweden - Buprenorphine Sandoz
Sandoz, Denmark; Sandoz, Sweden - Buprénorphine Sandoz
Sandoz, France - Buprenorphine Teva
Teva, Sweden - Buprénorphine Teva
Teva Santé, France - Buprenorphine Wildlife Pharma [veterinary use]
Wildlife Pharma, South Africa - Buprenorphine/Naloxone [+ Naloxone]
G.L. Pharma GmbH, United Kingdom; Mylan, United Kingdom - Buprenorphin-HEXAL
Hexal, Germany - Buprenorphinhydrochlorid API
Caesar & Loretz, Germany - Buprenorphin-Mepha
Mepha Pharma, Switzerland - Buprenovet [veterinary use]
Bayer Vital, Germany - Bupresol [veterinary use]
CPPharma, Germany - Bupretec 35 μ/h
G.L. Pharma, Austria - Buprevet [veterinary use]
Richter Pharma Austria, United Kingdom - Buprex
Quintiles, Spain - Buprexone-ZN [+ Naloxone]
Zdorovie, Georgia - Busansil
Angelini, Portugal - Cizdol-N [+ Naloxone]
Maan, Georgia - Cizdol-N Plus [+ Naloxone]
Maan, Georgia - Dorfene
Pharmedic, Pakistan - Dorgesic
Dosaco, Pakistan - Editax-N [+ Naloxone]
Omega Pharma, Georgia - Espranor
Martindale, United Kingdom; Martindale, Malta; Unimedic, Sweden - Gesnor
PDH, Pakistan - Herbane
Psicofarma, Mexico - Ilium Temvet [veterinary use]
Ilium Veterinary Products, Australia - Molterfin
Molteni Farmaceutici, Sweden - Mommi
Xenon, Pakistan - Mylan-Buprenorphine/Naloxone [+ Naloxone]
Mylan Pharmaceuticals, Canada - Norvipren
Sandoz, Denmark - PMS-Buprenorphine-Naloxone [+ Naloxone]
Pharmascience, Canada - Prefibin
Sandoz, United Kingdom - Prenorvine
Rafarm, Greece - Probuphine
TITAN, United States - Ravata
Heaton, Czech Republic - SBT
Rafa, Israel - Sha Fei
Tianjin Institute of Pharmaceutical Research Pharmaceutical, China - Shumeifen
Livzon Pharmaceutical Factory, China - Suboxone [+ Naloxone]
Indivior, Australia; Indivior, Bosnia & Herzegowina; Indivior, Czech Republic; Indivior, Denmark; Indivior, Spain; Indivior, Ireland; Indivior, Norway; Indivior, Sweden; Indivior, United States; Indivior France, France; Indivior UK, Belgium; Indivior UK, Canada; Indivior UK, Finland; Indivior UK, United Kingdom; Indivior UK, Lithuania; Indivior UK, Romania; Indivior UK Limited, Iceland; Indivior UK, Portugal; Merck Sharp & Dohme, Hong Kong; Pharmacy Retailing, New Zealand; Reckitt Benckiser, Estonia; Reckitt Benckiser, Indonesia; Reckitt Benckiser, Poland; Reckitt Benckiser, Slovakia; Reckitt Benckiser, Taiwan; Schering-Plough, South Africa - Suboxone 16mg/4mg [+ Naloxone]
Indivior UK Ltd, Germany - Suboxone 2mg/0.5mg [+ Naloxone]
Indivior, Israel; Indivior UK, Austria; Indivior UK Ltd, Germany; RB Pharmaceuticals, Hungary; Reckitt Benckiser Healthcare, Luxembourg - Suboxone 8mg/2mg [+ Naloxone]
Indivior, Israel; Indivior UK, Austria; Indivior UK Ltd, Germany; Reckitt Benckiser Healthcare, Luxembourg - Subuphine
Activase, Sweden - Subutex
Essex Italia, Italy; Farmavita, Croatia (Hrvatska); Indivior, Australia; Indivior, Czech Republic; Indivior, Denmark; Indivior, Ireland; Indivior, Sweden; Indivior Europe, Latvia; Indivior France, France; Indivior UK, Belgium; Indivior UK, United Kingdom; Indivior UK, Portugal; Reckitt Benckiser, Malta; Reckitt Benckiser, Taiwan; Schering-Plough, Indonesia; Schering-Plough, South Africa; Indivior UK, Lithuania - Subutex 0,4mg
Indivior UK Ltd, Germany - Subutex 0.4mg
Indivior, Switzerland - Subutex 2mg
Indivior, Switzerland; Indivior, Israel; Indivior UK, Austria; Indivior UK Ltd, Germany; Reckitt Benckiser Healthcare, Luxembourg - Subutex 8mg
Indivior, Switzerland; Indivior, Israel; Indivior UK, Austria; Indivior UK Ltd, Germany; Reckitt Benckiser Healthcare, Luxembourg - Tecnopren
Tecnofarma, Mexico - Temgesic
Brocacef, Netherlands; Indivior, Australia; Indivior, Denmark; Indivior, Netherlands; Indivior, Norway; Indivior, Sweden; Indivior UK, Belgium; Indivior UK, Finland; Indivior UK, United Kingdom; Indivior UK Ltd, Germany; Medcor Pharmaceuticals, Netherlands; Merck Sharp & Dohme, Hong Kong; Merck Sharp & Dohme, Mexico; Pharmacy Retailing, New Zealand; Reckitt Benckiser, Taiwan; Schering-Plough, Italy; Schering-Plough, South Africa - Temgésic
Indivior France, France - Temgesic 0.2mg
Indivior, Switzerland; Indivior UK, Luxembourg; RB Pharmaceuticals, Austria - Temgesic 0.3mg/ml
Indivior, Switzerland; Indivior UK, Luxembourg - Temgesic 0.4mg
Indivior, Switzerland; RB Pharmaceuticals, Austria - Temgesic Forte
Indivior UK Ltd, Germany - Tephine
Sandoz, United Kingdom - Vetergesic [veterinary use]
Alstoe, Norway; Ceva Animal Health, United Kingdom; Orion Pharma Animal Health, Sweden; Orion Pharma Eläinlääkkeet, Finland - Vetergesic 0.3 mg/ml [veterinary use]
Ceva Sante Animale, Netherlands; Sogeval, France - Vetergesic vet [veterinary use]
Ceva Santé Animale, Iceland; Sogeval, Poland - ZUBSOLV [+ Naloxone]
Orexo, United States
Glossary
Term | Definition |
---|---|
BAN | British Approved Name |
BANM | British Approved Name (Modified) |
DCF | Dénomination Commune Française |
DCIT | Denominazione Comune Italiana |
IUPAC | International Union of Pure and Applied Chemistry |
IS | Inofficial Synonym |
JAN | Japanese Accepted Name |
OS | Official Synonym |
PH | Pharmacopoeia Name |
Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
USAN | United States Adopted Name |
WHO | World Health Organization |
Further information on drug naming conventions: International Nonproprietary Names.
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Further information
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