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Buprenorphine

In some countries, this medicine may only be approved for veterinary use.

In the US, Buprenorphine (buprenorphine systemic) is a member of the drug class narcotic analgesics and is used to treat Chronic Pain, Opiate Dependence and Pain.

US matches:

UK matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

N02AE01,N07BC01,N07BC51

CAS registry number (Chemical Abstracts Service)

0052485-79-7

Chemical Formula

C29-H41-N-O4

Molecular Weight

467

Therapeutic Category

Opioid analgesic

Chemical Names

(5R,6R,6R,7R,9R,13S,14S)-17-Cyclopropylmetyl-7-[(S)-3,3-dimetyl-2-hydroxybutan-2-yl-]-6-metoxy-4,5-epoxy-6,14-etanomorphinan-3-ol (IUPAC)

21-Cyclopropyl-7alpha-[(S)-1-hydroxy-1,2,2-trimetylpropyl]-6,14-endo-etano-6,7,8,14-tetrahydrooripavine (WHO)

6,14-Etenomorphinan-7-metanol, 17-(cyclopropylmetyl)-α-(1,1-dimetyletyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-metoxy-α-metyl-, [5α,7α(S)]-

Foreign Names

Generic Names

  • Buprenorfina (OS: DCIT)
  • Buprenorphine (OS: BAN, JAN)
  • Buprénorphine (OS: DCF)
  • 6029-M (IS: ReckittColma)
  • Buprenorphin (PH: Ph. Eur. 8)
  • Buprenorphine (PH: BP 2016, Ph. Eur. 8)
  • Buprénorphine (PH: Ph. Eur. 8)
  • Buprenorphinum (PH: Ph. Eur. 8)
  • Buprenorphine Hydrochloride (OS: BANM, USAN, JAN)
  • CL 112302 (IS: Lederle)
  • NIH 8805 (IS)
  • RX 6029-M (IS: ReckittColma)
  • UM 952 (IS)
  • Buprénorphine (chlorhydrate de) (PH: Ph. Eur. 8)
  • Buprenorphine Hydrochloride (PH: BP 2016, JP XVI, USP 38)
  • Buprenorphine hydrochloride (PH: Ph. Eur. 8)
  • Buprenorphinhydrochlorid (PH: Ph. Eur. 8)
  • Buprenorphini hydrochloridum (PH: Ph. Eur. 8)

Brand Names

  • Addictex
    Actavis, Malta; Actavis UK, United Kingdom
  • Addnok
    Activase Pharmaceuticals, Slovenia
  • Addnok-N (Buprenorphine and Naloxone)
    Rusan Pharma Ltd., Georgia
  • Astec
    Gebro Pharma, Austria
  • Bunavail (Buprenorphine and Naloxone)
    BDSI, United States
  • Bunondol
    Polfa Warszawa, Poland; Warszawskie Zaklady Farmaceutyczne Polfa, Lithuania
  • BUP-4 Tagepflaster Libra-Pharm
    Libra-Pharm, Germany
  • Buprecare (veterinary use)
    Animalcare, Netherlands
  • Buprendal
    G.L. Pharma, Poland
  • Buprenorfin Alkaloid
    Alkaloid, Serbia
  • Buprenorfin Sandoz
    Sandoz, Croatia (Hrvatska)
  • Buprenorfina Molteni
    Molteni Dental, Italy
  • Buprenorfine Ranbaxy
    Ranbaxy, Netherlands
  • Buprenorphin AWD
    AWD.pharma, Germany
  • Buprenorphine Alkaloid
    Alkaloid, Poland
  • Buprenorphine G.L.
    G.L. Pharma, Lithuania
  • Buprenorphine Martindale
    Martindale, Malta
  • Buprenorphine Orifarm
    Orifarm, Norway
  • Buprenorphine Sandoz
    Sandoz AS, Norway
  • Buprenorphin-Mepha
    Mepha Pharma, Switzerland
  • Buprenorphin-ratiopharm
    ratiopharm, Germany
  • Buprinor
    AstraZeneca, India
  • Butrans
    LTS Lohmann Therapie Systeme, Israel; Mundipharma, Ireland; Napp Pharmaceuticals, United Kingdom; Purdue, United States
  • BuTrans
    Mundipharma, Netherlands; Purdue Pharma, Canada
  • Feliben
    Gebro, Spain
  • Hapoctasin
    Actavis UK, United Kingdom
  • Kennaf
    Actavis Group, Poland
  • Lepetan
    Otsuka Pharmaceutical, Japan
  • Natzon
    Morningside Healthcare, Malta
  • Norspan
    Grünenthal, Germany; Mundipharma, Austria; Mundipharma, China; Mundipharma, Estonia; Mundipharma, Finland; Mundipharma, Hong Kong; Mundipharma, Hungary; Mundipharma, Japan; Mundipharma, Lithuania; Mundipharma, Norway; Mundipharma, New Zealand; Mundipharma, Philippines; Mundipharma, Sweden; norpharma, Denmark
  • Ramatrix
    Tecnimede, Portugal
  • Simbadol (veterinary use)
    Abbott, United States
  • Soloro
    Grünenthal, Mexico
  • Sovenor
    Mundipharma, Malaysia; Mundipharma, Singapore; Mundipharma, South Africa
  • Suboxone (Buprenorphine and Naloxone)
    Reckitt Benckiser, Norway; Reckitt Benckiser Healthcare UK, Bosnia & Herzegowina; Schering-Plough, Turkey
  • Subutex
    Reckitt Benckiser, Norway
  • Temgesic
    Schering-Plough, Tunisia
  • Transtec
    Grünenthal, Austria; Grünenthal, Belgium; Grünenthal, Switzerland; Grünenthal, Czech Republic; Grünenthal, Ecuador; Grünenthal, Spain; Grünenthal, Hungary; Grünenthal, Mexico; Grünenthal, Netherlands; Grünenthal, Peru; Grünenthal, Poland; Grünenthal, Portugal; Grünenthal, Slovakia; Grünenthal Chilena, Chile; Grünenthal Italia, Italy; Mundipharma, Ireland; Napp Pharmaceuticals, United Kingdom; norpharma, Denmark; Stada, Croatia (Hrvatska)
  • Transtec PRO
    Grünenthal, Germany
  • Triquisic
    Grünenthal, Portugal
  • Vetergesic (veterinary use)
    Alstoe, United Kingdom; Ceva Sante Animale, Ireland; Sogeval SA, United Kingdom
  • Vetergesic chiens, chats (veterinary use)
    Sogeval Laboratoire, Belgium
  • Zalban
    Nisshin Pharmaceutical, Japan
  • Addictex
    Actavis Group, Cyprus
  • Belbuca
    Endo, United States
  • Brospina
    Pisa, Mexico
  • Buepron
    Sami, Pakistan
  • Bunondol
    Polfa Warsaw, Latvia
  • Bunorfin
    Atco, Pakistan; Molteni, Poland
  • Bupaq (veterinary use)
    Richter Pharma, Austria; Richter Pharma, United Kingdom; Richter Pharma, Norway; Richter Pharma AG, Ireland; Salfarm, Sweden; Streuli Vet, Switzerland; Vetcare, Finland; Virbac, Germany; Virbac, France
  • Bupensan
    G.L. Pharma, Austria; G.L. Pharma, Estonia
  • Buprecare (veterinary use)
    Animalcare, United Kingdom; Animalcare, Ireland; Animalcare, Netherlands; Axience, France
  • Bupregesic
    Popular, Pakistan
  • Buprenaddict
    Hexal, Germany
  • Buprenex
    Reckitt Benckiser, United States
  • Buprenodale (veterinary use)
    Albrecht, Germany; Dechra, Ireland; Dechra, Netherlands; Dechra Veterinary Products, Belgium; Dechra Veterinary Products, United Kingdom
  • Buprenorfin Actavis
    Actavis, Sweden
  • Buprenorfin Alkaloid
    Alkaloid, Bosnia & Herzegowina; Alkaloid, Croatia (Hrvatska); Alkaloid, Macedonia
  • Buprenorfin Evolan
    Evolan, Sweden
  • Buprenorfina Actavis
    Actavis, Portugal
  • Buprenorfina Azevedos
    Azevedos, Portugal
  • Buprenorfina Goldfarma
    Goldfarma, Portugal
  • Buprenorfina Sun
    SUN Pharmac.Italia, Italy
  • Buprenorfine Fisher
    Fisher Farma, Netherlands
  • Buprenorfine Mylan
    Mylan, Netherlands
  • Buprenorfine SUN
    Sun Pharma, Netherlands
  • Buprenorphin AbZ
    AbZ-Pharma, Germany
  • Buprenorphin Actavis
    Actavis, Bulgaria; Actavis, Denmark
  • Buprenorphin HEXAL
    Hexal, Germany; Hexal Pharma, Austria
  • Buprenorphin Teva
    Teva, Denmark
  • Buprenorphine
    Shinlin Sinseng, Taiwan
  • Buprenorphine Actavis
    Actavis UK, United Kingdom
  • Buprenorphine Alkaloid
    Alkaloid, Bulgaria; Alkaloid, Czech Republic
  • Buprénorphine Arrow
    Arrow, France
  • Buprénorphine Biogaran
    Biogaran, France
  • Buprenorphine Bluefish
    Bluefish Pharma, Sweden
  • Buprénorphine EG
    EG Labo, France
  • Buprenorphine G.L.
    G.L. Pharma, Bulgaria
  • Buprenorphine Hydrochloride Hospira
    Hospira, United States
  • Buprenorphine Morningside
    Morningside Healthcare, Malta
  • Buprénorphine Mylan
    Mylan, France
  • Buprenorphine Orifarm
    Orifarm Generics, Denmark; Orifarm Generics, Sweden
  • Buprenorphine Sandoz
    Sandoz, Denmark; Sandoz, Sweden
  • Buprénorphine Sandoz
    Sandoz, France
  • Buprenorphine Teva
    Teva, Sweden
  • Buprénorphine Teva
    Teva Santé, France
  • Buprenorphine Wildlife Pharma (veterinary use)
    Wildlife Pharma, South Africa
  • Buprenorphin-HEXAL
    Hexal, Germany
  • Buprenorphin-Mepha
    Mepha Pharma, Switzerland
  • Buprenorphin-neuraxpharm
    neuraxpharm, Germany
  • Buprenorphin-ratiopharm
    ratiopharm, Germany
  • Buprenovet (veterinary use)
    Animalcare, Austria; Bayer, Germany
  • Buprex
    Quintiles, Spain
  • Gabup
    Martindale Pharmaceuticals, United Kingdom
  • Loxina
    L. Molteni & Alitti, Portugal
  • Norvipren
    Sandoz, Denmark
  • Prefibin
    Sandoz, United Kingdom
  • Prenorvine
    Rafarm, Greece
  • Ravata
    Heaton, Czech Republic
  • SBT
    Rafa, Israel
  • Sha Fei
    Tianjin Institute of Pharmaceutical Research Pharmaceutical, China
  • Shumeifen
    Livzon Zhuhai, China
  • Suboxone (Buprenorphine and Naloxone)
    Farmavita, Croatia (Hrvatska); Merck Sharp & Dohme, Hong Kong; RB Pharmaceuticals, Austria; RB Pharmaceuticals, Canada; RB Pharmaceuticals, Germany; RB Pharmaceuticals, Spain; RB Pharmaceuticals, Finland; RB Pharmaceuticals, France; RB Pharmaceuticals, United Kingdom; RB Pharmaceuticals, Greece; RB Pharmaceuticals, Hungary; RB Pharmaceuticals, Ireland; RB Pharmaceuticals, Israel; RB Pharmaceuticals, Sweden; Rb Pharmaceuticals-UK, Italy; Reckitt Benckiser, Australia; Reckitt Benckiser, Belgium; Reckitt Benckiser, Czech Republic; Reckitt Benckiser, Denmark; Reckitt Benckiser, Indonesia; Reckitt Benckiser, Iceland; Reckitt Benckiser, Netherlands; Reckitt Benckiser, New Zealand; Reckitt Benckiser, Poland; Reckitt Benckiser, Portugal; Reckitt Benckiser, Slovakia; Reckitt Benckiser, Taiwan; Reckitt Benckiser, United States; Schering-Plough, Lithuania; Schering-Plough, Latvia; Schering-Plough, Romania; Schering-Plough, South Africa
  • Subutex
    Farmavita, Croatia (Hrvatska); RB Pharmaceuticals, Austria; RB Pharmaceuticals, Germany; RB Pharmaceuticals, France; RB Pharmaceuticals, United Kingdom; RB Pharmaceuticals, Ireland; RB Pharmaceuticals, Israel; RB Pharmaceuticals, Sweden; RB Pharmaceuticals Limited, Portugal; Rb Pharmaceuticals-UK, Italy; Reckitt Benckiser, Australia; Reckitt Benckiser, Belgium; Reckitt Benckiser, Switzerland; Reckitt Benckiser, Denmark; Reckitt Benckiser, Malta; Reckitt Benckiser, Taiwan; Reckitt Benckiser, United States; Schering-Plough, Czech Republic; Schering-Plough, Indonesia; Schering-Plough, Latvia; Schering-Plough, South Africa; Schering-Plough, Lithuania
  • Tecnopren
    Tecnofarma, Mexico
  • Temgesic
    Fisher Farma, Netherlands; Indivior, Netherlands; Merck Sharp & Dohme, Hong Kong; RB Pharmaceuticals, Austria; RB Pharmaceuticals, Finland; RB Pharmaceuticals, United Kingdom; RB Pharmaceuticals, Sweden; RB Pharmaceuticals-UK, Italy; Reckitt Benckiser, Belgium; Reckitt Benckiser, Switzerland; Reckitt Benckiser, Denmark; Reckitt Benckiser, Netherlands; Reckitt Benckiser, Norway; Reckitt Benckiser, New Zealand; Reckitt Benckiser, Taiwan; Schering-Plough, South Africa
  • TEMGESIC
    RB Pharmaceuticals, Germany
  • Temgésic
    RB Pharmaceuticals, France
  • TEMGESIC forte
    RB Pharmaceuticals, Germany
  • Tephine
    Sandoz, United Kingdom
  • Vetergesic (veterinary use)
    Alstoe, Netherlands; Alstoe, Norway; Ecuphar, Germany; Orion Pharma Animal Health, Sweden; Sogeval, France; Orion Pharma Eläinlääkkeet, Finland
  • ZUBSOLV (Buprenorphine and Naloxone)
    Orexo, United States

International Drug Name Search

Glossary

TermDefinition
BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Important Notice: The Drugs.com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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