Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- eculizumab
- Octagam (immune globulin intravenous)
Interactions between your drugs
immune globulin intravenous eculizumab
Applies to: Octagam (immune globulin intravenous), eculizumab
According to the prescribing information for eculizumab, intravenous immunoglobulin (IVIg) treatment may interfere with the endosomal neonatal Fc receptor (FcRn) recycling mechanism of monoclonal antibodies such as eculizumab, which may lead to decreased serum concentrations of eculizumab. The clinical significance is unknown. Drug interaction studies have not been conducted with eculizumab in patients treated with IVIg.
References (3)
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- (2007) "Product Information. Soliris (eculizumab)." Alexion Pharmaceuticals Inc
- Cerner Multum, Inc. "Australian Product Information."
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Empaveli
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Ultomiris
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Enspryng
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Zilbrysq
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Rystiggo
Rystiggo is used to treat generalized myasthenia gravis (gMG) in adults who are acetylcholine ...
Mestinon
Mestinon (pyridostigmine) is used to increase muscle strength in conditions such as myasthenia ...
Vyvgart
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Further information
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