Drug Interaction Report
28 potential interactions and/or warnings found for the following 2 drugs:
- Disophrol (dexbrompheniramine / pseudoephedrine)
- Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Interactions between your drugs
atropine chlorpheniramine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Using atropine together with chlorpheniramine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
atropine phenylephrine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Atropine may increase the effects of phenylephrine on your blood pressure and heart rate. Before receiving these medications, you should let your doctor know if you have high blood pressure or heart disease. You may not be able to use one or both of these medications, or you may need closer monitoring by your doctor in order to use these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
atropine hyoscyamine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Using atropine together with hyoscyamine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
atropine scopolamine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Using atropine together with scopolamine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
atropine dexbrompheniramine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Disophrol (dexbrompheniramine / pseudoephedrine)
Using atropine together with dexbrompheniramine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
chlorpheniramine hyoscyamine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Using chlorpheniramine together with hyoscyamine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
chlorpheniramine scopolamine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Using chlorpheniramine together with scopolamine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
chlorpheniramine dexbrompheniramine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Disophrol (dexbrompheniramine / pseudoephedrine)
Using chlorpheniramine together with dexbrompheniramine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phenylephrine phenylpropanolamine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Both phenylephrine and phenylpropanolamine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phenylephrine pseudoephedrine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Disophrol (dexbrompheniramine / pseudoephedrine)
Both phenylephrine and pseudoephedrine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phenylephrine hyoscyamine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Hyoscyamine may increase the effects of phenylephrine on your blood pressure and heart rate. Before receiving these medications, you should let your doctor know if you have high blood pressure or heart disease. You may not be able to use one or both of these medications, or you may need closer monitoring by your doctor in order to use these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phenylephrine scopolamine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Scopolamine may increase the effects of phenylephrine on your blood pressure and heart rate. Before receiving these medications, you should let your doctor know if you have high blood pressure or heart disease. You may not be able to use one or both of these medications, or you may need closer monitoring by your doctor in order to use these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phenylpropanolamine pseudoephedrine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Disophrol (dexbrompheniramine / pseudoephedrine)
Both phenylpropanolamine and pseudoephedrine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hyoscyamine scopolamine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Using hyoscyamine together with scopolamine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hyoscyamine dexbrompheniramine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Disophrol (dexbrompheniramine / pseudoephedrine)
Using hyoscyamine together with dexbrompheniramine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
scopolamine dexbrompheniramine
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine), Disophrol (dexbrompheniramine / pseudoephedrine)
Using scopolamine together with dexbrompheniramine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
chlorpheniramine food
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Alcohol can increase the nervous system side effects of chlorpheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with chlorpheniramine. Do not use more than the recommended dose of chlorpheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
phenylpropanolamine food
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Using phenylpropanolamine with alcohol can increase the risk of cardiovascular side effects such as increased heart rate, chest pain, or blood pressure changes. In addition, you may also be more likely to experience nervous system side effects such as dizziness, drowsiness, depression, and difficulty concentrating. You should avoid or limit the use of alcohol while being treated with phenylpropanolamine. Do not use more than the recommended dose of phenylpropanolamine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
dexbrompheniramine food
Applies to: Disophrol (dexbrompheniramine / pseudoephedrine)
Alcohol can increase the nervous system side effects of dexbrompheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dexbrompheniramine. Do not use more than the recommended dose of dexbrompheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
atropine food
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Ask your doctor before using atropine together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking atropine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hyoscyamine food
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Ask your doctor before using hyoscyamine together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking hyoscyamine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
scopolamine food
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Ask your doctor before using scopolamine together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking scopolamine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phenylephrine food
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Both phenylephrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phenylpropanolamine food
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Both phenylpropanolamine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
pseudoephedrine food
Applies to: Disophrol (dexbrompheniramine / pseudoephedrine)
Both pseudoephedrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
scopolamine food
Applies to: Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Antihistamines
Therapeutic duplication
The recommended maximum number of medicines in the 'antihistamines' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'antihistamines' category:
- Disophrol (dexbrompheniramine / pseudoephedrine)
- Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
Decongestants
Therapeutic duplication
The recommended maximum number of medicines in the 'decongestants' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'decongestants' category:
- Disophrol (dexbrompheniramine / pseudoephedrine)
- Rolatuss-SR (atropine / chlorpheniramine / hyoscyamine / phenylephrine / phenylpropanolamine / scopolamine)
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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