Drug Interaction Report
4 potential interactions and/or warnings found for the following 2 drugs:
- Anafranil (clomipramine)
- Pediatex 12 (carbinoxamine)
Interactions between your drugs
clomiPRAMINE carbinoxamine
Applies to: Anafranil (clomipramine), Pediatex 12 (carbinoxamine)
Using clomiPRAMINE together with carbinoxamine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
clomiPRAMINE food
Applies to: Anafranil (clomipramine)
Grapefruit, grapefruit juice, and cranberry juice may cause the clomiPRAMINE levels in your body to increase. This may lead to potentially dangerous adverse effects. If you are receiving clomiPRAMINE therapy and consume cranberry juice or grapefruit products, you should be monitored for adverse effects and changes in clomiPRAMINE levels. Do not increase or decrease the amount of cranberry juice or grapefruit products in your diet without first talking to your doctor.
carbinoxamine food
Applies to: Pediatex 12 (carbinoxamine)
Alcohol can increase the nervous system side effects of carbinoxamine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with carbinoxamine. Do not use more than the recommended dose of carbinoxamine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
clomiPRAMINE food
Applies to: Anafranil (clomipramine)
Ask your doctor before using clomiPRAMINE together with ethanol, this can alter the effects of clomiPRAMINE and increase the side effects. Call the doctor if you experience uneven heartbeats, extreme drowsiness, confusion, agitation, vomiting, blurred vision, sweating, muscle stiffness, feeling light-headed, and seizures. You should be warned not to exceed recommended dosages, to avoid alcohol, and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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