Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- calcium chloride
- digitoxin
Interactions between your drugs
digitoxin calcium chloride
Applies to: digitoxin, calcium chloride
GENERALLY AVOID: The administration of parenteral calcium preparations, particularly by rapid IV injection, may precipitate serious cardiac arrhythmias in digitalized patients. The mechanism is probably related to the additive or synergistic inotropic effects of calcium and digitalis glycosides on the myocardium.
MANAGEMENT: Intravenous calcium should preferably not be used in patients receiving digitalis glycosides, or it should be given slowly or in small amounts to avoid high serum calcium concentrations. Patients should be monitored for development of arrhythmias.
References (3)
- (2001) "Product Information. Lanoxin (digoxin)." Glaxo Wellcome
- (2001) "Product Information. Calcium Gluconate (calcium gluconate)." Fresenius Kabi USA, LLC
- (2001) "Product Information. PhosLo (calcium acetate)." Braintree
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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