Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- efgartigimod alfa / hyaluronidase
- prilocaine
Interactions between your drugs
hyaluronidase prilocaine
Applies to: efgartigimod alfa / hyaluronidase, prilocaine
When hyaluronidase is added to a local anesthetic, the local anesthetic solution undergoes increased absorption, resulting in a shorter duration of action and possible increased frequency of systemic reactions. The clinical significance is unknown. It may be advisable to monitor the patient for altered anesthetic efficacy and side effects.
References (2)
- (2004) "Product Information. Vitrase (hyaluronidase)." Bausch and Lomb Americas, Inc.
- (2023) "Product Information. Vyvgart Hytrulo (efgartigimod alfa-hyaluronidase)." argenx US Inc.
Drug and food/lifestyle interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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