Drug Interaction Report

If you are currently being treated with nifurtimox, let your doctor know before you receive fecal microbiota, live. Using nifurtimox together with fecal microbiota, live or 1 to 3 days before receiving treatment with fecal microbiota, live may decrease the effects of fecal microbiota, live. In addition, it may be advisable to avoid using any oral formulations of nifurtimox for 8 weeks after treatment with fecal microbiota, live. Your doctor may want to separate the dosing times by a few days or weeks to reduce the risk of an interaction, or they may want to monitor you more closely to make sure the medications are working as intended. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Consumption of alcoholic beverages or products containing alcohol during treatment with nifurtimox is not recommended. Doing so may occasionally trigger a reaction in some patients similar to the disulfiram reaction, which includes unpleasant effects such as flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion. Rarely, more severe reactions may include abnormal heart rhythm, heart attack, heart failure, unconsciousness, convulsions, and even death. Patients should take nifurtimox with food to ensure adequate absorption of the medication. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.