Drug Interaction Report

Bromfenac can affect kidney function and may increase the blood levels of DAPTOmycin when used together. Contact your doctor if you experience increased side effects or your condition changes. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should seek immediate medical attention if you have unexplained muscle pain, tenderness or weakness, especially if accompanied by fever or dark colored urine, as these may be signs and symptoms of a serious medical condition known as rhabdomyolysis that can occasionally occur during treatment with DAPTOmycin. Rhabdomyolysis involves the breakdown of skeletal muscle tissue and, in some cases, can cause kidney damage and even death. Also let your doctor know if you experience other symptoms that could indicate more serious problems such as cough, breathlessness, fever, and burning, tingling, or numbness in the hands and feet. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food significantly decreases the levels of bromfenac. Avoid eating a high-fat meal. Take bromfenac on an empty stomach at least 30 minutes before or 2 hours after a meal. This will make it easier for your body to absorb the medication.