Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- ginger / magnesium sulfate / pyridoxine
- levamlodipine
Interactions between your drugs
magnesium sulfate levamlodipine
Applies to: ginger / magnesium sulfate / pyridoxine, levamlodipine
MONITOR: Coadministration of intravenous magnesium and nifedipine may result in hypotension and neuromuscular blockade. Several cases have been reported in pregnant patients with preeclampsia. The mechanism is unknown. Other calcium channel blockers may also interact. The risk may be increased in patients with renal impairment.
MANAGEMENT: The cardiovascular, respiratory, and neurologic status of patients should be closely monitored if these drugs must be given concurrently.
References (7)
- Waisman GD, Mayorga LM, Camera MI, Vignolo CA, Martinotti A (1988) "Magnesium plus nifedipine: potentiation of hypotensive effect in preeclampsia?" Am J Obstet Gynecol, 159, p. 308-9
- Snyder SW, Cardwell MS (1989) "Neuromuscular blockade with magnesium sulfate and nifedipine." Am J Obstet Gynecol, 161, p. 35-6
- (2002) "Product Information. Adalat (nifedipine)." Bayer
- Benami M, Giladi Y, Shalev E (1994) "The combination of magnesium sulphate and nifedipine - a cause of neuromuscular blockade." Br J Obstet Gynaecol, 101, p. 262-3
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- Canadian Pharmacists Association (2006) e-CPS. http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink
- Briggs GG, Yaffe SJ., Freeman RK (2011) "Drugs in Pregnancy and Lactation." Philadelphia, PA: Llippincott Williams & Wilkins
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to consumer interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Diclegis
Diclegis (doxylamine and pyridoxine) is used to treat nausea and vomiting in pregnancy. Includes ...
Bonjesta
Bonjesta is used for nausea/vomiting, nausea/vomiting of pregnancy
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
CalciFolic-D
CalciFolic-D is used for vitamin/mineral supplementation and deficiency
Calcitrate with D
Calcitrate with D is used for dietary supplementation, osteoporosis
CitraNatal DHA
CitraNatal DHA is used for vitamin/mineral supplementation during pregnancy/lactation
CitraNatal Harmony
CitraNatal Harmony is used for vitamin/mineral supplementation during pregnancy/lactation
Concept DHA
Concept DHA is used for vitamin/mineral supplementation during pregnancy/lactation
Concept OB
Concept OB is used for vitamin/mineral supplementation during pregnancy/lactation
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.