Drug Interaction Report

Using panitumumab together with bevacizumab plus other chemotherapy drugs is generally not recommended. In clinical trials, combining these medications has led to a worse treatment outcome in terms of disease progression and survival rate than using bevacizumab alone plus other chemotherapy drugs. In addition, patients experienced more frequent and serious side effects including rash, dermatitis, diarrhea, dehydration, electrolyte imbalances, mouth ulcers or sores, and pulmonary embolism (blood clots in the lung). It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.