Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- voriconazole
- Zortress (everolimus)
Interactions between your drugs
voriconazole everolimus
Applies to: voriconazole, Zortress (everolimus)
Using everolimus together with voriconazole is not recommended. Combining these medications can significantly increase the blood levels of everolimus, which may make you more likely to develop serious side effects such as pneumonitis (inflammation of the lungs), infection, mouth ulcers, anemia, or bleeding. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
voriconazole food
Applies to: voriconazole
You may experience reduced absorption of voriconazole in the presence of food. Take voriconazole on an empty stomach 1 hour before or 2 hours after a meal unless otherwise directed by your doctor. This will make it easier for your body to absorb the medication.
everolimus food
Applies to: Zortress (everolimus)
Grapefruit juice can increase the blood levels and effects of everolimus. You should not drink grapefruit juice or eat grapefruits during your treatment with everolimus. Orange juice is not expected to interact.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Posaconazole is used for aspergillosis, invasive, candidemia, oral thrush
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Itraconazole
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Further information
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