Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- anagrelide
- Inocor I V (inamrinone)
Interactions between your drugs
inamrinone anagrelide
Applies to: Inocor I V (inamrinone), anagrelide
MONITOR: Anagrelide is an inhibitor of cyclic AMP phosphodiesterase (PDE) III and may potentiate the pharmacologic effects of drugs with similar properties such as inotropes milrinone, enoximone, inamrinone, olprinone, and cilostazol. Anagrelide alone has been associated with cardiovascular side effects such as vasodilation, palpitations, tachycardia, congestive heart failure, myocardial infarction, cardiomyopathy, cardiomegaly, complete heart block, and atrial fibrillation.
MANAGEMENT: Caution is advised if anagrelide is coadministered with other inotropes or PDE III inhibitors. The risk of potentially additive cardiovascular adverse effects should be considered.
References (1)
- (2001) "Product Information. Agrylin (anagrelide)." Roberts Pharmaceutical Corporation
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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