Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Rilutek (riluzole)
- tacrine
Interactions between your drugs
tacrine riluzole
Applies to: tacrine, Rilutek (riluzole)
It is not known if riluzole induces metabolic liver enzymes. Tacrine is metabolized by the same isoenzyme (CYP450 1A2) as riluzole. Theoretically, increased metabolism of tacrine could occur, leading to lower serum concentrations of tacrine. The clinical significance of this interaction is not known. Monitor this patient more closely for altered clinical effect.
References (1)
- (2001) "Product Information. Rilutek (riluzole)." Rhone Poulenc Rorer
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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