Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- amphotericin b liposomal
- netilmicin
Interactions between your drugs
netilmicin amphotericin B liposomal
Applies to: netilmicin, amphotericin b liposomal
MONITOR: The potential nephrotoxicity associated with amphotericin B and aminoglycosides may be additive.
MANAGEMENT: Just before the start and just before the end of each amphotericin infusion, hydration of the patient with 500 mL of normal saline may be helpful. The patient's renal function should be monitored frequently during therapy.
References (3)
- Churchill DN, Seely J (1977) "Nephrotoxicity associated with combined gentamicin - amphotericin B therapy." Nephron, 19, p. 176-81
- "Product Information. Abelcet (amphotericin B lipid complex)." Liposome Company Inc, The
- (2018) "Product Information. Arikayce (amikacin liposome)." Insmed Incorporated
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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