Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- lepirudin
- ticlopidine
Interactions between your drugs
ticlopidine lepirudin
Applies to: ticlopidine, lepirudin
MONITOR CLOSELY: Concomitant use of thrombin inhibitors and antiplatelet agents may increase the risk of bleeding complications due to additive or synergistic effects on the clotting cascade.
MANAGEMENT: Coadministration of thrombin inhibitors and antiplatelet agents should be undertaken with caution and only after thorough assessment of risks and benefits. Close clinical and laboratory observation for bleeding complications is recommended.
References (3)
- (2001) "Product Information. Refludan (lepirudin)." Hoechst Marion Roussel
- (2001) "Product Information. Acova (argatroban)." SmithKline Beecham
- (2001) "Product Information. Angiomax (bivalirudin)." The Medicines Company
Drug and food interactions
ticlopidine food
Applies to: ticlopidine
ADJUST DOSING INTERVAL: The bioavailability and gastrointestinal tolerance of ticlopidine is enhanced by food.
MANAGEMENT: Patients may be advised to take ticlopidine with meals.
References (1)
- (2001) "Product Information. Ticlid (ticlopidine)." Syntex Laboratories Inc
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Angiomax
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Pradaxa
Pradaxa (dabigatran) is used to prevent stroke and blood clots in patients with atrial ...
Taltz
Taltz (ixekizumab) is used to treat plaque psoriasis, psoriatic arthritis, and ankylosing ...
Dabigatran
Dabigatran systemic is used for deep vein thrombosis, deep vein thrombosis, prophylaxis, deep vein ...
Bivalirudin
Bivalirudin systemic is used for angina, percutaneous coronary intervention
Argatroban
Argatroban systemic is used for thrombotic/thromboembolic disorder
Further information
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