Drug Interaction Report

If you are using lactulose for the treatment of a condition known as portal-systemic encephalopathy, you should talk to your doctor before using it with psyllium. The loose stools produced by treatment with psyllium may make it difficult to know when you have achieved an adequate dosage of lactulose. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Psyllium may interact with other medications if given at the same time. This can cause your other medications to become less effective. In general, all oral medications should be administered at least 2 hours before or 2 hours after dosing of psyllium. Take psyllium with a full glass (at least 8 ounces) of cool water or another liquid. Taking psyllium without enough liquid may cause it to swell in the throat and cause choking.