Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- lactulose
- Magonate (magnesium carbonate)
Interactions between your drugs
lactulose magnesium carbonate
Applies to: lactulose, Magonate (magnesium carbonate)
Preliminary data from studies in humans and rats suggest that nonabsorbable antacids given concurrently with lactulose may inhibit the reduction in colonic pH induced by lactulose. Theoretically, this may reduce the effectiveness of lactulose in the treatment of portal-systemic encephalopathy, which requires an acidic environment in the colon to promote extraction of ammonia from the blood as well as retention/elimination of ammonia as the ammonium ion. However, the clinical relevance of this interaction has not been fully elucidated.
References (2)
- (2002) "Product Information. Chronulac (lactulose)." Hoechst Marion Roussel
- (2002) "Product Information. Cephulac (lactulose)." Hoechst Marion Roussel
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Constulose
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Enulose
Enulose is used for constipation, acute, constipation, chronic, hepatic encephalopathy
Duphalac
Duphalac is a laxative used to treat chronic constipation by drawing water into the colon ...
Kristalose
Kristalose is used for constipation, acute, constipation, chronic, hepatic encephalopathy
Generlac
Generlac is used for constipation, acute, constipation, chronic, hepatic encephalopathy
Neomycin
Neomycin is used for bowel preparation, diarrhea, hepatic coma, hepatic encephalopathy
Learn more
Further information
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