Drug Interaction Report

When use of sodium nitrite is required, the doctor should be told if you have been receiving treatment with alprostadil. Sodium nitrite can cause hypotension (low blood pressure), and the risk may be greater when combined with other medications that decrease blood pressure such as alprostadil. Excessively low blood pressure can lead to shock, collapse, coma, or even death. Your doctor will need to monitor you closely and possibly take extra precautions for you to safely use these medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.