Drug Interaction Report

Using ergocalciferol together with cholecalciferol should generally be avoided unless otherwise directed by your doctor. Both of these medications are forms of vitamin D, and taking too much vitamin D can lead to toxic effects related to excessive calcium levels in the blood and urine, such as irregular heart rhythm, seizures, kidney stones, and eventual calcification of blood vessels, cornea, and soft tissues of the body. If you take digoxin, a common heart medication, having a high blood level of calcium can also increase the risk of developing digoxin toxicity. Talk to your doctor if you have any questions or concerns. You will need close monitoring of your calcium and phosphorus levels to safely use these medications. You should avoid an abrupt increase in your dietary calcium intake, and seek medical attention if you experience early symptoms of vitamin D intoxication such as weakness, fatigue, headache, drowsiness, vertigo, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Late symptoms may include frequent urination, excessive thirst, weight loss, conjunctivitis ("pink eye"), light sensitivity, runny nose, itching, increased body temperature, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Food may reduce the absorption and blood levels of ferrous gluconate. In addition, some oral medications can also interfere with ferrous gluconate absorption into the bloodstream, which may make the medication less effective in treating your condition. Likewise, ferrous gluconate may interfere with the absorption of other orally administered medications. You should take ferrous gluconate on an empty stomach at least one hour before or two hours after a meal. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Talk to your doctor or pharmacist if you have questions about how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Food may reduce the absorption and blood levels of ferrous sulfate. In addition, some oral medications can also interfere with ferrous sulfate absorption into the bloodstream, which may make the medication less effective in treating your condition. Likewise, ferrous sulfate may interfere with the absorption of other orally administered medications. You should take ferrous sulfate on an empty stomach at least one hour before or two hours after a meal. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Talk to your doctor or pharmacist if you have questions about how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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The recommended maximum number of medicines in the 'nutritionals' category to be taken concurrently is usually three. Your list includes four medicines belonging to the 'nutritionals' category:

• ferrous sulfate
• Vitamin D3 (cholecalciferol)
• Vitamin D2 (ergocalciferol)
• ferrous gluconate

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

The recommended maximum number of medicines in the 'iron preparations' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'iron preparations' category:

• ferrous sulfate
• ferrous gluconate

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

The recommended maximum number of medicines in the 'vitamins and minerals' category to be taken concurrently is usually three. Your list includes four medicines belonging to the 'vitamins and minerals' category:

• ferrous sulfate
• Vitamin D3 (cholecalciferol)
• Vitamin D2 (ergocalciferol)
• ferrous gluconate

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

The recommended maximum number of medicines in the 'vitamin d analogs' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'vitamin d analogs' category:

• Vitamin D3 (cholecalciferol)
• Vitamin D2 (ergocalciferol)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.