Papaverine/phentolamine and Alcohol/Food Interactions
There are 3 alcohol/food/lifestyle interactions with papaverine / phentolamine.
Papaverine Alcohol (Ethanol)
Moderate Drug Interaction
Using papaverine and phentolamine together may lead to increased side effects, such as low blood pressure, dizziness, fainting, and/or priapism (prolonged and painful erection unrelated to sexual activity). Your doctor may already be aware of the risks but has determined that this is the best course of treatment for you, has taken appropriate precautions, and is monitoring you closely for any potential complications. Seek immediate medical attention if you experience an erection that lasts for more than 4 hours. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Papaverine Alcohol (Ethanol)
Moderate Drug Interaction
Papaverine and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Phentolamine Alcohol (Ethanol)
Moderate Drug Interaction
Phentolamine and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Switch to professional interaction data
Papaverine/phentolamine drug interactions
There are 396 drug interactions with papaverine / phentolamine.
Papaverine/phentolamine disease interactions
There are 5 disease interactions with papaverine / phentolamine which include:
- complete AV heart block
- cardiovascular dysfunction
- glaucoma
- cerebrovascular disorders
- hepatic/renal dysfunction
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.