Pafolacianine and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with pafolacianine.
Multivitamins With Minerals Pafolacianine
Major Drug Interaction
ADJUST DOSING INTERVAL: Concomitant administration of folate, folic acid, or folate-containing supplements may reduce the binding of pafolacianine to folate receptors overexpressed on ovarian cancer cells. This may lead to a reduction in the detection of malignant lesions with pafolacianine.
MANAGEMENT: Concomitant use of folate, folic acid, or folate-containing supplements with pafolacianine is not recommended. The manufacturer advises that these supplements should be discontinued 48 hours before the administration of pafolacianine.
References (1)
- (2021) "Product Information. Cytalux (pafolacianine)." Grand River Aseptic Manufacturing
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Pafolacianine drug interactions
There are 11 drug interactions with pafolacianine.
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- During pregnancy
- Drug class: malignancy photosensitizers
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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