Metreleptin and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with metreleptin.
Metreleptin Obesity
Major Potential Hazard, High plausibility
metreleptin - obesity
The use of metreleptin is contraindicated in patients with general obesity not associated with congenital leptin deficiency. Metreleptin has not been shown to be effective in treating general obesity. Moreover, development of anti-metreleptin antibodies with neutralizing activity has been reported in obese patients treated with metreleptin, the clinical consequences of which have not been well characterized but could include inhibition of endogenous leptin action and loss of metreleptin efficacy. Worsening metabolic control and/or severe infection have been reported.
Metreleptin drug interactions
There are 184 drug interactions with metreleptin.
Metreleptin disease interactions
There are 4 disease interactions with metreleptin which include:
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- Drug class: miscellaneous metabolic agents
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.