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Staphcillin and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Staphcillin (methicillin).

Moderate

Methicillin High Blood Pressure (Hypertension)

Moderate Potential Hazard, High plausibility

methicillin - sodium/potassium

Each gram of parenteral methicillin sodium contains approximately 60 to 71 mg (2.6 to 3.1 mEq) of sodium and is buffered with 50 mg of sodium citrate. The sodium content should be considered in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention. In addition, hypokalemia has been reported rarely during therapy with the penicillinase-resistant penicillins, which may be particularly important to bear in mind when treating patients with low potassium reserves or fluid and electrolyte imbalance. Clinical monitoring of electrolytes is recommended if these agents are used for prolonged periods.

References

  1. Schlaeffer F (1988) "Oxacillin-associated hypokalemia." Drug Intell Clin Pharm, 22, p. 695-6
  2. (2002) "Product Information. Staphcillin (methicillin)." Apothecon Inc
  3. Andreoli SP, Kleiman MB, Glick MR, Bergstein JM (1980) "Nafcillin, pseudoproteinuria, and hypokalemic alkalosis." J Pediatr, 97, p. 841-2

Staphcillin drug interactions

There are 33 drug interactions with Staphcillin (methicillin).

Staphcillin disease interactions

There are 5 disease interactions with Staphcillin (methicillin) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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