Cobimetinib and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with cobimetinib.
Cobimetinib Food
Moderate Food Interaction
Grapefruit juice may increase the blood levels and effects of certain medications such as cobimetinib. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with cobimetinib. However, if you have been regularly consuming grapefruit or grapefruit juice with cobimetinib, do not alter the amounts of these products in your diet without first talking to your doctor or other healthcare professional. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
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Cobimetinib drug interactions
There are 396 drug interactions with cobimetinib.
Cobimetinib disease interactions
There are 7 disease interactions with cobimetinib which include:
- cardiomyopathy
- hepatotoxicity
- ocular toxicities
- rhabdomyolysis
- lung toxicity
- liver dysfunction
- renal impairment
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- Drug class: multikinase inhibitors
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
