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Targretin and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with Targretin (bexarotene).

Moderate

Bexarotene Food

Moderate Food Interaction

Food helps with the absorption of bexarotene from the gastrointestinal tract into the blood stream. You should take each dose the same time everyday with a meal. Avoid consuming large amounts of grapefruit or grapefruit juice during treatment, since doing so may increase the blood levels of bexarotene. Talk to your doctor or pharmacist if you have any questions or concerns about your medication. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

Bexarotene High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)

Moderate Potential Hazard, Moderate plausibility

bexarotene - hyperlipidemia

The use of bexarotene may cause elevations in lipids. It is recommended to monitor lipid levels closely and to obtain a fasting blood lipid reading at baseline and weekly until lipid response to the drug is established. Exercise caution when using this agent in patients with hyperlipidemia.

References

  1. (2001) "Product Information. Targretin (bexarotene)." Ligand Pharmaceuticals

Targretin drug interactions

There are 617 drug interactions with Targretin (bexarotene).

Targretin disease interactions

There are 7 disease interactions with Targretin (bexarotene) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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