Talwin Compound and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Talwin Compound (aspirin / pentazocine).
Pentazocine Food/Lifestyle
Major Food Interaction
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Alcohol may potentiate the central nervous system (CNS) depressant effects of opioid analgesics including pentazocine. Concomitant use may result in additive CNS depression and impairment of judgment, thinking, and psychomotor skills. In more severe cases, hypotension, respiratory depression, profound sedation, coma, or even death may occur.
MONITOR CLOSELY: Smoking tobacco may decrease the plasma concentrations and effects of pentazocine by enhancing its metabolic clearance.
MANAGEMENT: Patients should not consume alcoholic beverages or use drug products that contain alcohol during treatment with pentazocine. Any history of alcohol or illicit drug use should be considered when prescribing pentazocine and therapy initiated at a lower dosage if necessary. Patients should be closely monitored for signs and symptoms of sedation, respiratory depression, and hypotension. Additionally, the possibility of reduced therapeutic effects of pentazocine should be considered if smoking cannot be avoided.
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Talwin Compound drug interactions
There are 729 drug interactions with Talwin Compound (aspirin / pentazocine).
Talwin Compound disease interactions
There are 23 disease interactions with Talwin Compound (aspirin / pentazocine) which include:
- coagulation
- impaired GI motility
- infectious diarrhea
- prematurity
- asthma
- gastrointestinal obstruction
- acute MI
- drug dependence
- intracranial pressure
- respiratory depression
- GI toxicity
- renal dysfunction
- Reye's syndrome
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- biliary tract disease
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.