Motrin Cold and Flu Interactions
There are 587 drugs known to interact with Motrin Cold and Flu (ibuprofen / pseudoephedrine), along with 17 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 116 are major, 451 are moderate, and 20 are minor.
- View all 587 medications that may interact with Motrin Cold and Flu
- View Motrin Cold and Flu alcohol/food interactions (3)
- View Motrin Cold and Flu disease interactions (17)
Most frequently checked interactions
View interaction reports for Motrin Cold and Flu (ibuprofen / pseudoephedrine) and the medicines listed below.
- acetaminophen
- acetaminophen
- acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine
- acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine
- Actos (pioglitazone)
- Actos (pioglitazone)
- Advil (ibuprofen)
- Advil (ibuprofen)
- Advil Allergy Sinus (chlorpheniramine / ibuprofen / pseudoephedrine)
- Advil Allergy Sinus (chlorpheniramine / ibuprofen / pseudoephedrine)
- Advil Migraine (ibuprofen)
- Advil Migraine (ibuprofen)
- Advil PM (diphenhydramine / ibuprofen)
- Advil PM (diphenhydramine / ibuprofen)
- albuterol
- albuterol
- Aleve (naproxen)
- Aleve (naproxen)
- Aleve-D Sinus & Cold (naproxen / pseudoephedrine)
- Aleve-D Sinus & Cold (naproxen / pseudoephedrine)
- Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate)
- Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate)
- Alka-Seltzer Plus Flu / Body (acetaminophen / dextromethorphan / pseudoephedrine)
- Alka-Seltzer Plus Flu / Body (acetaminophen / dextromethorphan / pseudoephedrine)
- Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels (acetaminophen / dextromethorphan / phenylephrine)
- Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels (acetaminophen / dextromethorphan / phenylephrine)
- Alka-Seltzer PM (calcium phosphate, tribasic / melatonin)
- Alka-Seltzer PM (calcium phosphate, tribasic / melatonin)
- Tylenol (acetaminophen)
- Tylenol (acetaminophen)
Motrin Cold and Flu alcohol/food interactions
There are 3 alcohol/food interactions with Motrin Cold and Flu (ibuprofen / pseudoephedrine).
Motrin Cold and Flu disease interactions
There are 17 disease interactions with Motrin Cold and Flu (ibuprofen / pseudoephedrine) which include:
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- cardiovascular disease
- PKU
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
Report options
More about Motrin Cold and Flu (ibuprofen / pseudoephedrine)
- Compare alternatives
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
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Ozempic
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Conex
Conex is used for allergic rhinitis, cold symptoms, nasal congestion, sinus symptoms
Alka-Seltzer Plus Cold
Alka-Seltzer Plus Cold is used for cold symptoms, sinus symptoms
Guaifenesin/phenylephrine
Guaifenesin/phenylephrine is used for cough and nasal congestion, sinus symptoms
Acetaminophen/dextromethorphan/phenylephrine
Acetaminophen/dextromethorphan/phenylephrine is used for cold symptoms, cough, cough and nasal ...
Naproxen/pseudoephedrine
Naproxen/pseudoephedrine is used for nasal congestion, pain/fever, sinus symptoms
Mometasone nasal
Mometasone nasal is used for allergic rhinitis, allergies, nasal polyps, sinus symptoms
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
