Hycomine Interactions
There are 719 drugs known to interact with Hycomine (hydrocodone / phenylpropanolamine), along with 21 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 244 are major, 472 are moderate, and 3 are minor.
- View all 719 medications that may interact with Hycomine
- View Hycomine alcohol/food interactions (2)
- View Hycomine disease interactions (21)
Most frequently checked interactions
View interaction reports for Hycomine (hydrocodone / phenylpropanolamine) and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- acetaminophen / hydrocodone
- Advil (ibuprofen)
- albuterol
- Aleve (naproxen)
- Allegra (fexofenadine)
- Allegra Allergy (fexofenadine)
- Aller-Tec (cetirizine)
- aluminum hydroxide
- amiloride
- Amitiza (lubiprostone)
- amitriptyline
- amlodipine
- amoxicillin
- ashwaganda
- atenolol
- Benadryl (diphenhydramine)
- cefdinir
- clonazepam
- doxycycline
- fluticasone nasal
- gabapentin
- licorice
- magnesium hydroxide
- Nexium 24HR (esomeprazole)
- omeprazole
- ondansetron
- pantoprazole
- propranolol
- tramadol
Hycomine alcohol/food interactions
There are 2 alcohol/food interactions with Hycomine (hydrocodone / phenylpropanolamine).
Hycomine disease interactions
There are 21 disease interactions with Hycomine (hydrocodone / phenylpropanolamine) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- psychosis
- BPH
- diabetes
- glaucoma
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.