Hydrocodone/phenylephrine/pyrilamine Interactions
There are 768 drugs known to interact with hydrocodone/phenylephrine/pyrilamine, along with 27 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 235 are major, 529 are moderate, and 4 are minor.
- View all 768 medications that may interact with hydrocodone/phenylephrine/pyrilamine
- View hydrocodone/phenylephrine/pyrilamine alcohol/food interactions (2)
- View hydrocodone/phenylephrine/pyrilamine disease interactions (27)
Most frequently checked interactions
View interaction reports for hydrocodone / phenylephrine / pyrilamine and the medicines listed below.
- Big Shot B-12 (cyanocobalamin)
- Botox (onabotulinumtoxinA)
- BuSpar (buspirone)
- Carisoprodol Compound (aspirin / carisoprodol)
- Celebrex (celecoxib)
- Diazepam Intensol (diazepam)
- Eliquis (apixaban)
- Flomax (tamsulosin)
- Frova (frovatriptan)
- Humalog KwikPen (insulin lispro)
- Hydrocodone CP (chlorpheniramine / hydrocodone / phenylephrine)
- Inderal (propranolol)
- Lantus (insulin glargine)
- Mobic (meloxicam)
- Nasonex (mometasone nasal)
- Ozempic (semaglutide)
- Paxil (paroxetine)
- Seroquel (quetiapine)
- Simponi Aria (golimumab)
- Topamax (topiramate)
- Toprol-XL (metoprolol)
- Voltaren (diclofenac)
- Wellbutrin (bupropion)
Hydrocodone/phenylephrine/pyrilamine alcohol/food interactions
There are 2 alcohol/food interactions with hydrocodone / phenylephrine / pyrilamine.
Hydrocodone/phenylephrine/pyrilamine disease interactions
There are 27 disease interactions with hydrocodone / phenylephrine / pyrilamine which include:
- depression
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- BPH
- diabetes
- glaucoma
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.