Drug Interactions between emtricitabine / tenofovir alafenamide and MSP-Blu
This report displays the potential drug interactions for the following 2 drugs:
- emtricitabine/tenofovir alafenamide
- MSP-Blu (hyoscyamine/methenamine/methylene blue/phenyl salicylate)
Interactions between your drugs
No interactions were found between emtricitabine / tenofovir alafenamide and MSP-Blu. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
emtricitabine / tenofovir alafenamide
A total of 234 drugs are known to interact with emtricitabine / tenofovir alafenamide.
- Emtricitabine / tenofovir alafenamide is in the drug class antiviral combinations.
- Emtricitabine / tenofovir alafenamide is used to treat the following conditions:
MSP-Blu
A total of 572 drugs are known to interact with MSP-Blu.
- Msp-blu is in the drug class urinary antispasmodics.
- Msp-blu is used to treat Urinary Tract Infection.
Drug and food interactions
hyoscyamine food
Applies to: MSP-Blu (hyoscyamine / methenamine / methylene blue / phenyl salicylate)
GENERALLY AVOID: Use of anticholinergic agents with alcohol may result in sufficient impairment of attention so as to render driving and operating machinery more hazardous. In addition, the potential for abuse may be increased with the combination. The mechanism of interaction is not established but may involve additive depressant effects on the central nervous system. No effect of oral propantheline or atropine on blood alcohol levels was observed in healthy volunteers when administered before ingestion of a standard ethanol load. However, one study found impairment of attention in subjects given atropine 0.5 mg or glycopyrrolate 1 mg in combination with alcohol.
MANAGEMENT: Alcohol should generally be avoided during therapy with anticholinergic agents. Patients should be counseled to avoid activities requiring mental alertness until they know how these agents affect them.
References
- Linnoila M "Drug effects on psychomotor skills related to driving: interaction of atropine, glycopyrrhonium and alcohol." Eur J Clin Pharmacol 6 (1973): 107-12
tenofovir food
Applies to: emtricitabine / tenofovir alafenamide
Food enhances the oral absorption and bioavailability of tenofovir, the active entity of tenofovir disoproxil fumarate. According to the product labeling, administration of the drug following a high-fat meal increased the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of tenofovir by approximately 14% and 40%, respectively, compared to administration in the fasting state. However, administration with a light meal did not significantly affect the pharmacokinetics of tenofovir compared to administration in the fasting state. Food delays the time to reach tenofovir Cmax by approximately 1 hour. Tenofovir disoproxil fumarate may be administered without regard to meals.
References
- "Product Information. Viread (tenofovir)." Gilead Sciences (2001):
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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