Can you take Clofazimine with Risa-Bid?
1 drug interaction and 5 additional warnings found for the following 2 drugs:
- clofazimine
- Risa-Bid (lactobacillus acidophilus)
Drug interactions
Moderate drug interactions
Moderate:
clofazimine lactobacillus acidophilus
Applies to: clofazimine and Risa-Bid (lactobacillus acidophilus)
Using clofazimine together with lactobacillus acidophilus may decrease the effects of lactobacillus acidophilus when these medications are taken at the same time. To prevent or minimize the interaction, lactobacillus acidophilus should be administered at least 2 hours before or after clofazimine. Contact your doctor if you have any concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease interactions
5 potential interactions Applies to: 5 conditions, including Diarrhea, Inflammatory Bowel Disease, Liver Disease, Immunodeficiency, and Renal Dysfunction.
Diarrhea
Moderate:
clofazimine
Clofazimine has a moderate potential interaction with Diarrhea.
The use of clofazimine has been associated with severe abdominal symptoms including splenic infarction, bowel obstruction, and GI bleeding. Death has been reported following severe abdominal symptoms. Crystalline deposits have been found in the intestinal mucosa, liver, gallbladder, bile, spleen, adrenals, subcutaneous fat, mesenteric lymph nodes, muscles, bone and skin. Clofazimine should be administered cautiously in patients with GI problems such as abdominal pain and diarrhea.
Immunodeficiency
Moderate:
Risa-Bid
The lactobacillus acidophilus in Risa-Bid has a moderate potential interaction with Immunodeficiency.
Probiotics, especially those containing lactobacillus, should be used with caution in immunosuppressed patients.
Inflammatory Bowel Disease
Moderate:
clofazimine
Clofazimine has a moderate potential interaction with Inflammatory Bowel Disease.
The use of clofazimine has been associated with severe abdominal symptoms including splenic infarction, bowel obstruction, and GI bleeding. Death has been reported following severe abdominal symptoms. Crystalline deposits have been found in the intestinal mucosa, liver, gallbladder, bile, spleen, adrenals, subcutaneous fat, mesenteric lymph nodes, muscles, bone and skin. Clofazimine should be administered cautiously in patients with GI problems such as abdominal pain and diarrhea.
Liver Disease
Moderate:
clofazimine
Clofazimine has a moderate potential interaction with Liver Disease.
Use of clofazimine should be avoided in patients with hepatic dysfunction (Child-Pugh A, B, or C).
Renal Dysfunction
Moderate:
clofazimine
Clofazimine has a moderate potential interaction with Renal Dysfunction.
Clofazimine should be used with caution in patients with severe renal dysfunction. No dose adjustments are recommended in patients with mild to moderate renal dysfunction.
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clofazimine
A total of 385 drugs are known to interact with clofazimine.
- Clofazimine is in the drug class leprostatics.
- Clofazimine is used to treat the following conditions:
Risa-Bid
A total of 370 drugs are known to interact with Risa-Bid.
- Risa-bid is in the following drug classes: antidiarrheals, probiotics.
- Risa-bid is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.