Drug Interactions between Champix and varenicline
This report displays the potential drug interactions for the following 2 drugs:
- Champix (varenicline)
- varenicline
Interactions between your drugs
No interactions were found between Champix and varenicline. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Champix
A total of 8 drugs are known to interact with Champix.
- Champix is in the following drug classes: cholinergic agonists, smoking cessation agents.
- Champix is used to treat Smoking Cessation.
varenicline
A total of 8 drugs are known to interact with varenicline.
- Varenicline is in the following drug classes: cholinergic agonists, smoking cessation agents.
- Varenicline is used to treat the following conditions:
Drug and food interactions
varenicline food
Applies to: Champix (varenicline) and varenicline
GENERALLY AVOID: Varenicline may enhance the effects of alcohol as well as alter the way an individual reacts to alcohol. During postmarketing use, some patients have reported experiencing increased intoxicating effects of alcohol while taking varenicline. In addition, some reported cases of neuropsychiatric events, including unusual and sometimes aggressive behavior directed toward oneself or others, may have been worsened by concomitant use of alcohol. These events were often accompanied by amnesia.
MANAGEMENT: Patients should be advised to limit their consumption of alcohol until they know whether varenicline affects their tolerance for alcohol, and to exercise caution driving or operating machinery until they know how quitting smoking and/or varenicline may affect them. Patients should immediately stop taking varenicline and contact their physician if they develop agitation, hostility, aggressive behavior, depressed mood, or changes in behavior or thinking that are not typical for them, or if they develop suicidal ideation or behavior.
References
- (2006) "Product Information. Chantix (varenicline)." Pfizer U.S. Pharmaceuticals Group
- FDA. U.S. Food and Drug Administration (2015) Drug Safety Communications: FDA updates label for stop smoking drug Chantix (varenicline) to include potential alcohol interaction, rare risk of seizures, and studies of side effects on mood, behavior, and thinking. Safety announcement. http://www.fda.go
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Nicotine-craving reduction agents
Therapeutic duplication
The recommended maximum number of medicines in the 'nicotine-craving reduction agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'nicotine-craving reduction agents' category:
- Champix (varenicline)
- varenicline
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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