Acetaminophen/caffeine/phenylpropanolamine/salicylamide Drug Interactions
Currently displaying a list of 515 drugs known to interact with acetaminophen / caffeine / phenylpropanolamine / salicylamide.
- 66 major drug interactions
- 401 moderate drug interactions
- 48 minor drug interactions
Medications known to interact with acetaminophen/caffeine/phenylpropanolamine/salicylamide
Note: Showing generic names only.
A
- abametapir topical
- acarbose
- acebutolol
- acetohexamide
- adenosine
- albiglutide
- albuterol
- alendronate
- aliskiren
- alogliptin
- alosetron
- amifampridine
- amikacin
- amikacin liposome
- amiloride
- aminophylline
- amitriptyline
- amobarbital
- amoxapine
- amphetamine
- anagrelide
- anisindione
- apalutamide
- apixaban
- apraclonidine ophthalmic
- ardeparin
- arformoterol
- argatroban
- armodafinil
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- aspirin
- atazanavir
- atenolol
- atezolizumab
- atomoxetine
- atropine
- avelumab
- azilsartan medoxomil
B
- bedaquiline
- belladonna
- benazepril
- bendamustine
- bendroflumethiazide
- benoxinate ophthalmic
- benzocaine topical
- benzphetamine
- benzthiazide
- benztropine
- betamethasone
- betaxolol
- betrixaban
- bexagliflozin
- biperiden
- bisoprolol
- bitolterol
- bivalirudin
- black cohosh
- brentuximab
- bromocriptine
- budesonide
- bumetanide
- bupivacaine
- bupivacaine liposome
- bupropion
- busulfan
- butabarbital
- butalbital
C
- calaspargase pegol
- canagliflozin
- candesartan
- cannabidiol
- capmatinib
- captopril
- carbamazepine
- carboplatin
- carteolol
- carvedilol
- cemiplimab
- ceritinib
- charcoal
- chloroprocaine
- chloroprocaine ophthalmic
- chlorothiazide
- chlorpromazine
- chlorpropamide
- chlorthalidone
- cholestyramine
- cimetidine
- cinoxacin
- ciprofloxacin
- citalopram
- clidinium
- clofarabine
- clomipramine
- clove
- clozapine
- cocaine nasal
- cocaine topical
- colchicine
- cortisone
- cosibelimab
- cycloserine
- cyclosporine
D
- dabigatran
- daclizumab
- dalteparin
- danaparoid
- dapagliflozin
- darifenacin
- deferasirox
- deflazacort
- delafloxacin
- deserpidine
- desipramine
- desirudin
- desvenlafaxine
- dexamethasone
- dexfenfluramine
- dexmethylphenidate
- dextroamphetamine
- diazepam
- dibucaine topical
- dicumarol
- dicyclomine
- diethylpropion
- diflunisal
- digitoxin
- digoxin
- dihydroergotamine
- dimethyl fumarate
- dipyridamole
- diroximel fumarate
- disulfiram
- divalproex sodium
- dobutamine
- dopamine
- dostarlimab
- doxapram
- doxepin
- doxepin topical
- drospirenone
- drotrecogin alfa
- droxidopa
- dulaglutide
- duloxetine
- durvalumab
E
- echinacea
- edoxaban
- efavirenz
- empagliflozin
- enalapril
- enalaprilat
- encorafenib
- enoxacin
- enoxaparin
- ephedrine
- epinephrine
- epirubicin
- eplerenone
- epoprostenol
- eprosartan
- ergonovine
- ergotamine
- ertugliflozin
- escitalopram
- esketamine
- esmolol
- ethacrynic acid
- ethanol
- ethinyl estradiol
- ethotoin
- etidocaine
- etidronate
- etranacogene dezaparvovec
- evening primrose
- exenatide
F
- fenfluramine
- fenofibrate
- fenoldopam
- fexinidazole
- fezolinetant
- fidanacogene elaparvovec
- flavoxate
- fludrocortisone
- fluoxetine
- fluphenazine
- fluvoxamine
- fondaparinux
- formoterol
- fosinopril
- fosphenytoin
- furazolidone
- furosemide
G
- gatifloxacin
- gemifloxacin
- gentamicin
- ginkgo
- givosiran
- glimepiride
- glipizide
- glyburide
- glycerol phenylbutyrate
- glycopyrrolate
- grepafloxacin
- guanadrel
- guanethidine
H
- haloperidol
- heparin
- hyaluronidase
- hydralazine
- hydrochlorothiazide
- hydrocortisone
- hydroflumethiazide
- hydroxyprogesterone
- hyoscyamine
I
- ibandronate
- idelalisib
- iloprost
- imatinib
- imipramine
- indacaterol
- indapamide
- indomethacin
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, live
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- interferon beta-1a
- interferon beta-1b
- iobenguane I 123
- iobenguane I 131
- ioflupane I 123
- iohexol
- iomeprol
- iopamidol
- ipilimumab
- irbesartan
- isocarboxazid
- isoetharine
- isoniazid
- isoproterenol
K
L
- labetalol
- landiolol
- leflunomide
- leniolisib
- lepirudin
- levalbuterol
- levobupivacaine
- levodopa
- levofloxacin
- levoketoconazole
- levomilnacipran
- levothyroxine
- lidocaine
- lidocaine ophthalmic
- lidocaine otic
- lidocaine topical
- linagliptin
- lindane topical
- linezolid
- liothyronine
- liraglutide
- lisdexamfetamine
- lisinopril
- lithium
- lixisenatide
- lomefloxacin
- lomitapide
- lorcaserin
- lorlatinib
- losartan
M
- ma huang
- mavorixafor
- mazindol
- mecamylamine
- melatonin
- mepenzolate
- mephentermine
- mephenytoin
- mephobarbital
- mepivacaine
- mesoridazine
- metaproterenol
- metaraminol
- metformin
- methamphetamine
- methdilazine
- methohexital
- methotrexate
- methotrimeprazine
- methoxamine
- methscopolamine
- methyclothiazide
- methyldopa
- methylene blue
- methylergonovine
- methylphenidate
- methylprednisolone
- methysergide maleate
- metoclopramide
- metolazone
- metoprolol
- metrizamide
- mibefradil
- midodrine
- miglitol
- milnacipran
- mipomersen
- modafinil
- moexipril
- momelotinib
- monomethyl fumarate
- moxifloxacin
N
- nadolol
- nalidixic acid
- naltrexone
- nateglinide
- nebivolol
- netilmicin
- nicotine
- niraparib
- nivolumab
- norepinephrine
- norfloxacin
- nortriptyline
O
- obeticholic acid
- ofloxacin
- olaparib
- olmesartan
- olodaterol
- olutasidenib
- omaveloxolone
- osilodrostat
- osimertinib
- ospemifene
- oxazepam
- oxybutynin
- oxytocin
- ozanimod
P
- pacritinib
- pamidronate
- paroxetine
- pegaspargase
- peginterferon beta-1a
- pembrolizumab
- pemetrexed
- penbutolol
- penpulimab
- pentobarbital
- perindopril
- perphenazine
- pexidartinib
- phendimetrazine
- phenelzine
- phenobarbital
- phentermine
- phenylephrine
- phenytoin
- pimozide
- pindolol
- pioglitazone
- pirbuterol
- piroxicam
- pirtobrutinib
- pitolisant
- plazomicin
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 7-valent vaccine
- polyethylene glycol 3350 with electrolytes
- polythiazide
- pralsetinib
- pramlintide
- pramoxine topical
- prednisolone
- prednisone
- primidone
- probenecid
- procaine
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propantheline
- proparacaine ophthalmic
- propiomazine
- propranolol
- protriptyline
- pseudoephedrine
Q
R
- racepinephrine
- ramelteon
- ramipril
- ranitidine
- ranitidine bismuth citrate
- rasagiline
- rauwolfia serpentina
- regadenoson
- remdesivir
- repaglinide
- reserpine
- retifanlimab
- rifampin
- riluzole
- risedronate
- ritlecitinib
- ritodrine
- rivaroxaban
- ropinirole
- ropivacaine
- rosiglitazone
- rucaparib
S
- safinamide
- salmeterol
- saxagliptin
- scopolamine
- secobarbital
- selegiline
- selexipag
- semaglutide
- sertraline
- sibutramine
- sitagliptin
- sodium salicylate
- solifenacin
- sotagliflozin
- sotalol
- sparfloxacin
- sparsentan
- spironolactone
- stiripentol
- streptomycin
- sulfinpyrazone
T
- tafamidis
- tapentadol
- telmisartan
- terbinafine
- terbutaline
- teriflunomide
- tetracaine
- tetracaine ophthalmic
- tetracaine topical
- theophylline
- thiabendazole
- thiethylperazine
- thioguanine
- thiopental
- thioridazine
- thyroid desiccated
- tiludronate
- timolol
- tinzaparin
- tirzepatide
- tislelizumab
- tizanidine
- tobramycin
- tolazamide
- tolbutamide
- tolterodine
- topotecan
- toripalimab
- torsemide
- trabectedin
- tramadol
- trandolapril
- tranylcypromine
- tremelimumab
- treprostinil
- triamcinolone
- triamcinolone ophthalmic
- triamterene
- trichlormethiazide
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimipramine
- troglitazone
- trospium
- trovafloxacin
V
- valoctocogene roxaparvovec
- valproic acid
- valsartan
- vamorolone
- varenicline
- varicella virus vaccine
- vemurafenib
- venlafaxine
- vilazodone
- viloxazine
- voclosporin
- vortioxetine
W
Z
Acetaminophen/caffeine/phenylpropanolamine/salicylamide alcohol/food interactions
There are 5 alcohol/food interactions with acetaminophen / caffeine / phenylpropanolamine / salicylamide.
Acetaminophen/caffeine/phenylpropanolamine/salicylamide disease interactions
There are 23 disease interactions with acetaminophen / caffeine / phenylpropanolamine / salicylamide which include:
- alcoholism
- liver disease
- cardiac disease
- hypertension
- psychiatric disorders
- PUD
- GI toxicity
- Reye's syndrome
- cardiovascular disease
- PKU
- cardiotoxicity
- liver disease
- renal dysfunction
- seizure disorders
- GERD
- psychosis
- anemia
- coagulation
- G-6-PD deficiency
- hepatotoxicity
- BPH
- diabetes
- glaucoma
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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