NK1 receptor antagonists
What are NK1 receptor antagonists?
Neurokinin-1 (NK1) receptor antagonists are used for prevention of acute and delayed nausea and vomiting. The NK1 receptor antagonist competitively binds to the NK1 receptor, which blocks the binding of substance P and prevents the emetic signal being transmitted. NK1 receptor antagonists can be used in conjunction with 5-HT3-receptor antagonists and corticosteroids to augment their antiemetic activity.
List of NK1 receptor antagonists:
|Drug Name||Reviews||Avg. Ratings|
|fosaprepitant systemic (Pro)||1 review||Add rating|
|aprepitant systemic (Pro)||17 reviews||8.0|
|rolapitant systemic (Pro)||1 review||10|
|For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).|
Medical conditions associated with NK1 receptor antagonists:
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