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Vorinostat Dosage

Medically reviewed on August 4, 2017.

Applies to the following strengths: 100 mg

Usual Adult Dose for Cutaneous T-cell Lymphoma

400 mg orally once daily with food

Treatment may be continued as long as there is no evidence of progressive disease or unacceptable toxicity.

Vorinostat capsules should not be opened or crushed.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

If this patient is intolerant to therapy, the dose may be reduced to 300 mg orally once daily with food. The dose may then be further reduced to 300 mg once daily with food for five consecutive days each week, as necessary.


Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).


Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.