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Tivicay Dosage

Generic name: DOLUTEGRAVIR SODIUM 10mg
Dosage form: tablet, film coated

The information at is not a substitute for medical advice. Always consult your doctor or pharmacist.


TIVICAY tablets may be taken with or without food.

Table 1. Dosing Recommendations for TIVICAY in Adult Patients


Recommended Dose

Treatment-naïve or treatment-experienced INSTI-naïve

50 mg once daily

Treatment-naïve or treatment-experienced INSTI-naïve when coadministered with certain UGT1A or CYP3A inducers [see Drug Interactions (7.3)]

50 mg twice daily

INSTI-experienced with certain INSTI-associated resistance substitutions or clinically suspected INSTI resistancea [see Microbiology (12.4)]

50 mg twice daily

a Alternative combinations that do not include metabolic inducers should be considered where possible [see Drug Interactions (7)].

Pediatric Patients

TIVICAY tablets may be taken with or without food.

Treatment-Naïve or Treatment-Experienced INSTI-Naïve

The recommended dose of TIVICAY in pediatric patients weighing at least 30 kg is provided in Table 2.

Table 2. Dosing Recommendations for TIVICAY in Pediatric Patients Weighing at Least 30 kg

Body Weight (kg)

Daily Dosea
(Number of Tablets per Dose when Different Strength(s) are Required)

30 to less than 40

35 mg once daily
(One 25-mg tablet and one 10-mg tablet)

40 or greater

50 mg once daily

a If certain UGT1A or CYP3A inducers are coadministered, then increase the weight-based dose of TIVICAY to twice daily [see Drug Interactions (7.3) for relevant inducers].

Safety and efficacy of TIVICAY have not been established in pediatric patients who are INSTI-experienced with documented or clinically suspected resistance to other INSTIs (raltegravir, elvitegravir).