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Ripretinib Dosage

Medically reviewed by Drugs.com. Last updated on Sep 23, 2022.

Applies to the following strengths: 50 mg

Usual Adult Dose for Gastrointestinal Stromal Tumor

Recommended dose: 150 mg orally once daily until disease progression or acceptable toxicity

Use: For the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Recommended dose reduction for adverse reactions: 100 mg orally once daily.


PALMAR-PLANTAR ERYTHRODYSESTHESIA SYNDROME (PPES):


HYPERTENSION:


LEFT VENTRICULAR SYSTOLIC DYSFUNCTION:

ARTHRALGIA OR MYALGIA:


OTHER ADVERSE REACTIONS:

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Storage requirements:

Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.