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Pyrantel Dosage

Medically reviewed by Drugs.com. Last updated on Dec 12, 2019.

Applies to the following strengths: 144 mg/mL (50 mg/mL base); 180 mg; base 50 mg/mL

Usual Adult Dose for Enterobiasis

11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose

Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose

Comments:
-Recommended as a regimen for E vermicularis (pinworm) infection
-This dose should be repeated in 2 weeks.
-Since family members are usually infected, the entire household should be treated; retreatment after 14 to 21 days may be necessary.
-Current guidelines should be consulted for additional information.

Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)

11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose

Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose

Comments:
-Recommended as a regimen for E vermicularis (pinworm) infection
-This dose should be repeated in 2 weeks.
-Since family members are usually infected, the entire household should be treated; retreatment after 14 to 21 days may be necessary.
-Current guidelines should be consulted for additional information.

Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)

Some Experts Recommend: 11 mg/kg base orally once a day for 3 days
Maximum dose: 1 g/dose

Comments:
-Recommended as a regimen for A duodenale and N americanus
-Current guidelines should be consulted for additional information.

Usual Adult Dose for Trichostrongylosis

Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose

Comments:
-Recommended for Trichostrongylus infection
-Current guidelines should be consulted for additional information.

Usual Adult Dose for Moniliformis Infection

Some Experts Recommend: 11 mg/kg base orally every 2 weeks for 3 doses

Comments:
-Recommended for Moniliformis moniliformis infection
-Current guidelines should be consulted for additional information.

Usual Pediatric Dose for Enterobiasis

2 years or older: 11 mg/kg base once as a single dose
Maximum dose: 1 g/dose

Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose

Comments:
-Recommended as a regimen for E vermicularis (pinworm) infection
-This dose should be repeated in 2 weeks.
-Since family members are usually infected, the entire household should be treated; retreatment after 14 to 21 days may be necessary.
-Current guidelines should be consulted for additional information.

Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)

2 years or older: 11 mg/kg base once as a single dose
Maximum dose: 1 g/dose

Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose

Comments:
-Recommended as a regimen for E vermicularis (pinworm) infection
-This dose should be repeated in 2 weeks.
-Since family members are usually infected, the entire household should be treated; retreatment after 14 to 21 days may be necessary.
-Current guidelines should be consulted for additional information.

Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)

Some Experts Recommend: 11 mg/kg base orally once a day for 3 days
Maximum dose: 1 g/dose

Comments:
-Recommended as a regimen for A duodenale and N americanus
-Current guidelines should be consulted for additional information.

Usual Pediatric Dose for Trichostrongylosis

Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose

Comments:
-Recommended for Trichostrongylus infection
-Current guidelines should be consulted for additional information.

Usual Pediatric Dose for Moniliformis Infection

Some Experts Recommend: 11 mg/kg base orally every 2 weeks for 3 doses

Comments:
-Recommended for M moniliformis infection
-Current guidelines should be consulted for additional information.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Comments:
-According to manufacturers, this drug should not be used in patients with liver disease unless directed by a physician.

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Dose expressed as pyrantel base.

Administration advice:
-Can administer at any time of day, with or without meals; may administer alone or with milk or juice
-Can mix the oral suspension with milk or fruit juice
-Shake oral suspension well before use.

Storage requirements:
-Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F).
-Do not freeze.

General:
-Pyrantel pamoate 144 mg is equivalent to 50 mg pyrantel base.
-Use of a laxative is not necessary before, during, or after administration of this drug.

Patient advice:
-Read the package insert/product information carefully before use.
-Administer only according to directions; do not exceed recommended dose unless directed by physician.
-Administer 1 time as a single dose; do not repeat treatment unless directed by physician.

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.