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Goprelto Dosage

Generic name: cocaine hydrochloride 40mg in 1mL
Dosage form: nasal solution
Drug class: Topical anesthetics

Medically reviewed by Last updated on Aug 8, 2023.

Important Dosage and Administration Instructions

  • GOPRELTO is for intranasal use only.
  • Do not apply GOPRELTO to damaged nasal mucosa.

Dosing Recommendation for Adults

The recommended dose of GOPRELTO is two soaked cottonoid pledgets placed in each nasal cavity, equivalent to 40 mg cocaine hydrochloride per pledget, for a total dose of 160 mg for four pledgets.

The total dose for any one procedure or surgery should not exceed 160 mg, or 3 mg/kg, cocaine hydrochloride.

The recommended size of cottonoid pledgets for use with GOPRELTO measure 1.3 cm × 4 cm (sold separately).

Preparation and Administration of GOPRELTO Pledgets

Pour the full contents of one 4 mL (160 mg) bottle of GOPRELTO into a small container. Soak four cottonoid pledgets until the solution is fully absorbed.

Following soaking, place two pledgets in each nasal cavity against the septum.

Leave pledgets in place for up to twenty minutes. Remove pledgets and continue with the procedure. Discard pledgets and dispose of any unused portion of solution in accordance with institutional procedures for CII products.

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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.