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Fluocinolone / Hydroquinone / Tretinoin Topical Dosage

Applies to the following strength(s): 0.01%-4%-0.05%

The information at is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Melasma

Apply thin film to hyperpigmented areas and 1/2 inch of surrounding skin once daily at night, at least 30 minutes before bedtime.

Wash face and neck and pat skin dry before applying.

Duration: Treatment may continue intermittently for up to 6 months of cumulative drug exposure.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended


Do not apply occlusive dressings.

Sodium metabisulfite ingredient may cause severe allergic reactions or asthmatic episodes in sensitive patients.

Avoid contact with eyes, mouth, mucous membranes, and open wounds.

Do not apply if skin is sunburned. Avoid exposure to sunlight and sunlamps. Apply an SPF 30 sunscreen during the day and wear protective clothing.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).


No adjustment recommended

Other Comments

May apply moisturizers and cosmetics during the day.