Ecallantide Dosage
Medically reviewed by Drugs.com. Last updated on Jun 4, 2024.
Applies to the following strengths: 10 mg/mL
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Hereditary Angioedema
30 mg subcutaneously in three 10 mg injections; may repeat an additional 30 mg within 24 hours if attack persists.
Usual Pediatric Dose for Hereditary Angioedema
12 years and older: 30 mg subcutaneously in three 10 mg injections; may repeat an additional 30 mg within 24 hours if attack persists.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
US BOXED WARNING:
- ANAPHYLAXIS: Anaphylaxis has been reported after administration of this drug. Because of the risk of anaphylaxis, this drug should only be administered by a healthcare professional with appropriate medical support to manage anaphylaxis and hereditary angioedema. Healthcare professionals should be aware of the similarity of symptoms between hypersensitivity reactions and hereditary angioedema and patients should be monitored closely. Do not administer this drug to patients with known clinical hypersensitivity to the active component.
Safety and efficacy have not been established in patients younger than 12 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- This drug should only be administered by a healthcare professional with appropriate medical support to manage anaphylaxis and hereditary angioedema.
- The manufacturer product information should be consulted.
Storage requirements:
- Protect from light.
- Refrigerate at 2 to 8C (36 to 46F). Vials removed from refrigeration should be stored below 30C (86F) and used within 14 days or returned to refrigeration until use.
Reconstitution/preparation techniques: The manufacturer product information should be consulted.
Monitoring: Monitor patients closely for hypersensitivity reactions.
Frequently asked questions
More about ecallantide
- Compare alternatives
- Reviews (2)
- Side effects
- During pregnancy
- Drug class: hereditary angioedema agents
- Breastfeeding
- En español
Patient resources
Other brands
Professional resources
Other brands
Related treatment guides
See also:
Berinert
Berinert is used to treat acute abdominal, facial, or laryngeal hereditary angioedema (HAE) attacks ...
Kalbitor
Kalbitor is used to treat acute attacks of hereditary angioedema (HAE) in patients 12 years and ...
Orladeyo
Orladeyo (berotralstat) is used to prevent attacks of hereditary angioedema (HAE). Includes ...
Haegarda
Haegarda is an injectable protein replacement therapy that prevents swelling and attacks in ...
Takhzyro
Takhzyro (lanadelumab-flyo) is used to prevent hereditary angioedema (HAE) and reduce symptoms ...
Firazyr
Firazyr is used to treat acute attacks of hereditary angioedema (HAE) in adults. It can be ...
Cinryze
Cinryze (complement C1 esterase inhibitor) is used to prevent attacks of angioedema in people with ...
Ruconest
Ruconest is used to treat angioedema attacks in adult and adolescent patients with Hereditary ...
Icatibant
Icatibant is an injection used to treat acute attacks of hereditary angioedema (HAE) in adults. It ...
Stanozolol
Stanozolol is used in the treatment of hereditary angioedema, which causes episodes of swelling of ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.