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Cerliponase Alfa Dosage

Medically reviewed by Last updated on May 25, 2023.

Applies to the following strengths: 150 mg/5 mL

Usual Pediatric Dose for Neuronal Ceroid Lipofuscinosis

3 years or older: 300 mg by intraventricular infusion once every other week


Use: To slow the loss of ambulation in symptomatic pediatric patients 3 years or older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl peptidase 1 (TPP1) deficiency

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available



Safety and efficacy have not been established in patients younger than 3 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

Storage requirements:
unopened vials in the refrigerator at 2C to 8C (36F to 46F) and use within 24 hours
syringes in the refrigerator at 2C to 8C (36F to 46F) up to 4 hours prior to infusion

Reconstitution/preparation techniques:


Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.