Generic name: CLOSTRIDIUM TETANI TOXOID ANTIGEN (FORMALDEHYDE INACTIVATED) 5[iU] in 0.5mL, CORYNEBACTERIUM DIPHTHERIAE TOXOID ANTIGEN (FORMALDEHYDE INACTIVATED) 2.5[iU] in 0.5mL, BORDETELLA PERTUSSIS TOXOID ANTIGEN (FORMALDEHYDE, GLUTARALDEHYDE INACTIVATED) 8ug in 0.5mL, BORDETELLA PERTUSSIS FILAMENTOUS HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED) 8ug in 0.5mL, BORDETELLA PERTUSSIS PERTACTIN ANTIGEN (FORMALDEHYDE INACTIVATED) 2.5ug in 0.5mL
Dosage form: injection, suspension
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Preparation for Administration
Shake vigorously to obtain a homogeneous, turbid, white suspension before administration. Do not use if resuspension does not occur with vigorous shaking. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. If either of these conditions exists, the vaccine should not be administered. BOOSTRIX should not be combined through reconstitution or mixed with any other vaccine.
Do not administer this product intravenously, intradermally, or subcutaneously.
BOOSTRIX is administered as a single 0.5-mL intramuscular injection into the deltoid muscle of the upper arm.
There are no data to support repeat administration of BOOSTRIX.
Five years should elapse between the last dose of the recommended series of Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed (DTaP) and/or Tetanus and Diphtheria Toxoids Adsorbed For Adult Use (Td) vaccine and the administration of BOOSTRIX.
Additional Dosing Information
Primary Series: The use of BOOSTRIX as a primary series or to complete the primary series for diphtheria, tetanus, or pertussis has not been studied.
Wound Management: Clinicians should refer to guidelines for tetanus prophylaxis in routine wound management.1 Individuals who have completed a primary series against tetanus and who sustain wounds which are minor and uncomplicated should receive a booster dose of a tetanus toxoid-containing vaccine only if they have not received tetanus toxoid within the preceding 10 years. In case of tetanus-prone injury (e.g., wounds contaminated with dirt, feces, soil, and saliva; puncture wounds; avulsions; and wounds resulting from missiles, crushing, burns, and frostbite) in an individual who is in need of tetanus toxoid, BOOSTRIX can be used as an alternative to Td vaccine in patients for whom the pertussis component is also indicated.
More about Boostrix (Tdap) (diphtheria toxoid / pertussis, acellular / tetanus toxoid)
- Other brands: Adacel (Tdap)
- Boostrix (FDA)
- Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed, Tetanus Toxoid and Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed (AHFS Monograph)