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Antithrombin Iii Dosage

Applies to the following strengths: 500 intl units; 1000 intl units

Usual Adult Dose for Antithrombin III Deficiency

Loading dose / target an antithrombin (AT) level of 120% of normal: 120% - baseline AT % x weight (in kg) / 1.4%

Dose adjustment (as needed) / target AT levels of 80 to 120% of normal: Target % - trough AT % x weight (in kg) / 1.4%

Maintenance dose / target AT levels of 80% to 120% of normal: Loading dose x 0.6 approximately every 24 hours


Use: Treatment and prevention of thromboembolism, including prevention of peri-operative and peri-partum thromboembolism in patients with hereditary antithrombin deficiency.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available



Safety and efficacy have not been established in patients younger than 18 years.
This drug is not recommended for use in children.

Consult WARNINGS section for additional precautions.


Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.