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ActHIB Dosage

Dosage form: solution for intramuscular injection

Medically reviewed by Last updated on Jun 6, 2019.

For intramuscular use only

Immunization Series

ActHIB vaccine is administered as a four-dose series (0.5 mL per dose) as:

  • A primary three-dose series of a single dose at 2, 4, and 6 months of age.
  • A single booster dose at 15 through 18 months of age.


ActHIB vaccine is a solution for injection supplied as single-dose vials of lyophilized vaccine to be reconstituted only with the accompanying saline diluent (0.4% Sodium Chloride). To reconstitute ActHIB vaccine, withdraw 0.6 mL of saline diluent and inject into the vial of lyophilized ActHIB vaccine. Agitate the vial to ensure complete reconstitution. The reconstituted ActHIB vaccine will appear clear and colorless. Withdraw a 0.5-mL dose of the reconstituted vaccine and inject intramuscularly. After reconstitution, if ActHIB vaccine is not administered promptly store at 2° to 8°C (35° to 46°F) and administer within 24 hours. Stored vaccine should be re-agitated prior to injection. Refer to Figures 1, 2, 3, and 4.

Instructions for Reconstitution of ActHIB Vaccine with Saline Diluent (0.4% Sodium Chloride)
Figure 1 Figure 2 Figure 3 Figure 4
Figure 1.
Disinfect the diluent vial stopper, inject the needle and withdraw 0.6 mL of 0.4% Sodium Chloride diluent as indicated.
Figure 2.
Cleanse the ActHIB vaccine stopper, insert the syringe needle into the vial, and inject the total volume of diluent.
Figure 3.
Agitate vial thoroughly.
Figure 4.
After reconstitution, withdraw 0.5 mL of reconstituted vaccine and administer intramuscularly.


Parenteral drug products should be inspected visually for particulate matter and/or discoloration prior to administration, whenever solution and container permit. If either of these conditions exist, the vaccine should not be administered.

ActHIB vaccine is administered as a single dose (0.5 mL) by intramuscular injection into the anterolateral aspect of the thigh or deltoid. Discard unused portion.

Do not administer this product intravenously, intradermally, or subcutaneously.

ActHIB vaccine should not be mixed in the same syringe with other parenteral products.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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