Skip to Content

Dojolvi

Generic Name: triheptanoin (oral liquid)

Medically reviewed by Judith Stewart, BPharm Last updated on Jun 30, 2020.

What is Dojolvi?

Dojolvi is a prescription medicine used to treat long-chain fatty acid oxidation disorders (LC-FAOD) in children and adults.

Before taking Dojolvi

Before taking Dojolvi, tell your healthcare provider about all of your medical conditions, including if you:

  • are pregnant or plan to become pregnant. It is not known if this medicine will harm your unborn baby.
    Pregnancy Safety Study. There is a pregnancy safety study for women who take Dojolvi during pregnancy.
    The purpose of this study is to collect information about your health and your baby’s health. You can talk to your
    healthcare provider or contact 1-888-756-8657 to enroll in this study or get more information.
  • are breastfeeding or plan to breastfeed. It is not known if this medicine passes into breast milk. Talk to your healthcare provider about the best way to feed your baby if you take Dojolvi.
  • are taking a pancreatic lipase inhibitor, such as orlistat, as it may affect how well Dojolvi works.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I take Dojolvi?

  • See the detailed Instructions for Use at the end of this Patient Information Leaflet for instructions about how to mix and take Dojolvi by mouth in soft foods or drinks or how to mix and give Dojolvi through feeding tubes.
  • Take this medicine exactly as your healthcare provider tells you.
  • Your healthcare provider may start you on a low dose, and slowly increase your dose to help avoid side effects. If you are taking another medium chain triglyceride (MCT) product, stop taking the MCT before starting Dojolvi.
  • Do not mix or give Dojolvi using containers, dosing syringes or measuring cups made of polystyrene (a type of plastic that can be solid or foam) or polyvinyl chloride (PVC), a solid plastic material.
  • Dojolvi should be taken at least 4 times a day with meals or snacks, and always mixed well with soft food or drink.

Dojolvi side effects

  • Feeding tube problems. Feeding tubes may not work as well or stop working over time when taking Dojolvi. Do not use Dojolvi in feeding tubes made of polyvinyl chloride (PVC). Monitor the feeding tube to make sure it is working properly.
  • Intestinal absorption problems in patients with pancreatic insufficiency. If you have pancreatic insufficiency, consult with your healthcare provider as it may affect how well Dojolvi works.

The most common side effects include:

  • stomach (abdominal) pain
  • diarrhea
  • vomiting
  • nausea

These are not all the possible side effects. Call your healthcare provider for medical advice about side effects. You may report side effects to Ultragenyx at 1-888-756-8657 or FDA at 1-800-FDA-1088.

How should I store Dojolvi?

  • Store Dojolvi at room temperature between 68°F to 77°F (20°C - 25°C).
  • Do not freeze Dojolvi.
  • When the bottle of Dojolvi has been opened, use within 90 days or by the expiration date on the bottle, whichever comes first.
  • Do not store Dojolvi in containers made of polystyrene or polyvinyl chloride (PVC).

Keep all medicines out of the reach of children and pets.

General information about the safe and effective use of Dojolvi.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information Leaflet. Do not use this medicine for a condition for which it was not prescribed. Do not give it to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information that is written for health professionals.

What are the ingredients in Dojolvi?

Dojolvi is made of 100% triheptanoin and contains no other ingredients.

Instructions for Use

Read this Instructions for Use before you start taking Dojolvi and each time you get a refill. There may be new information. This leaflet does not take the place of talking to your healthcare provider about your medical condition or treatment.

Important information about Dojolvi:

  • Use an oral syringe or measuring cup to measure your prescribed dose. Ask your healthcare provider or pharmacist to show you how to measure your prescribed dose.
  • Mix or give Dojolvi using containers, dosing syringes or measuring cups made of materials such as stainless steel, glass, or high-density polyethylene (HDPE), polypropylene, low density polyethylene, polyurethane and silicone (types of plastic materials).
  • Do not mix or give Dojolvi using containers, dosing syringes or measuring cups of polystyrene (a type of plastic that can be solid or foam) or polyvinyl chloride (PVC), a solid plastic material.
  • Dojolvi should be taken at least 4 times a day with meals or snacks, and always mixed well with soft food or drink.
  • Dojolvi can be mixed with the following soft food or drink:
    • plain or artificially sweetened fat free yogurt
    • fat free milk, formula or cottage cheese
    • whole grain hot cereal
    • fat free low carbohydrate pudding, smoothies, applesauce, or baby food
  • The mixture may be stored for up to 24 hours in the refrigerator.
  • Your healthcare provider may advise you on maintaining a proper diet when taking Dojolvi.
  • If you miss a dose, take the next dose as soon as possible. Take the following doses 3 to 4 hours apart. If it is not possible to take all the doses for the day, skip the missed dose.


Taking Dojolvi liquid by mouth:

  1. Use an oral syringe or measuring cup made of the materials listed above to measure the prescribed amount of Dojolvi from the bottle.
  2. Add the prescribed amount of Dojolvi to a clean bowl, cup, or container, made of the materials listed above, containing the appropriate amount of soft food or drink as instructed by your healthcare provider.
  3. Mix Dojolvi well into the soft food or liquid and swallow the mixture.
  4. The mixture may be stored for up to 24 hours in the refrigerator.

Giving Dojolvi liquid by feeding tube:

  1. Do not give Dojolvi in feeding tubes made of polyvinyl chloride (PVC), a type of plastic. Dojolvi can be given in feeding tubes made of silicone or polyurethane.
  2. Use an oral syringe or measuring cup made of the materials listed above to measure the correct dose from the bottle and mix with formula.
  3. Draw up the entire amount of the Dojolvi-formula mixture into a slip tip syringe.
  4. Remove the air from the syringe and connect the syringe directly into the feeding tube port.
  5. Push the contents of the syringe (Dojolvi-formula mixture) into the feeding tube port using steady pressure until empty.
  6. Draw up about 5 mL to 30 mL of water with the slip tip syringe and flush the feeding tube feeding port with the water. Throw away any unused Dojolvi-formula mixture. Do not save for later use.
  7. Check the feeding tube often to make sure it is working properly.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

More about Dojolvi (triheptanoin)

Related treatment guides